Health advisories and patterns of patient monitoring among new users of antidepressant medications.
Health advisories and patterns of patient monitoring among new users of antidepressant medications.
复制标题
抗抑郁药物新使用者的健康建议和患者监测模式。
DOI：
10.1097/jcp.0b013e3181bf4eb9
复制
发表时间：
2009
影响因子：
2.9
通讯作者：
Schneeweiss,Sebastian
中科院分区：
文献类型：
--
作者：
Gagne,JoshuaJ;Patrick,AmandaR;Wang,PhilipS;Schneeweiss,Sebastian
Materials and Methods:We conducted a cohort study of antidepressant initiators between 1999 and 2005 using healthcare utilization data of all British Columbia residents. For the periods before (1999-2001) and after (2004-2005), health advisories concerning suicidality associated with antidepressants, we assessed monitoring intensity by calculating weekly physician and psychotherapy visit rates since antidepressant initiation. We also estimated monitoring patterns as the proportion of individuals who received weekly in-person contact during the first 4 weeks of treatment, then biweekly visits for 4 weeks, and then a visit at 12 weeks, as a proxy for intensive monitoring.Results:Patterns of monitoring intensity were similar before and after the health advisories, but the level of intensity was lower after the advisory period. Overall, monitoring intensity peaked in the 4 weeks after antidepressant initiation. Weekly numbers of visits per subject during these 4 weeks were between 0.44 and 0.49 before the advisory and from 0.39 to 0.44 after the advisory. Among all initiators stratified by year of initiation, between 21% and 25% received intensive monitoring, and this proportion generally decreased on a yearly basis.Discussion:Monitoring intensity for patients with depression initiating antidepressants decreased after the period of emergence and greater awareness of the association between antidepressants and suicidality.
