Vagotomy attenuates suppression of sham feeding induced by intestinal nutrients.
Vagotomy attenuates suppression of sham feeding induced by intestinal nutrients.
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迷走神经切断术减弱了肠道营养物引起的假喂养的抑制。
DOI：
10.1152/ajpregu.1991.260.3.r503
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
Ritter,RC
中科院分区：
文献类型：
--
作者：
Yox,DP;Stokesberry,H;Ritter,RC
在完整大鼠和完全膈下迷走神经横断的大鼠中检查了肠内营养物输注抑制假喂养的能力。迷走神经切断术消除了通过肠内输注麦芽糖或油酸盐对假喂养的抑制。迷走神经切断术减少了肠内 L-苯丙氨酸对假喂养的抑制，但并未消除。该检查的结果表明，迷走神经通过肠内麦芽糖和油酸介导假喂养的抑制，但仅部分负责L-苯丙氨酸产生的食物摄入的抑制。与之前发表的数据结合起来，这些结果表明，特定营养素对进食的影响可能是由解剖学上不同的内脏传入神经元群体介导的。
The ability of intraintestinal nutrient infusions to suppress sham feeding was examined in intact rats and in rats with total subdiaphragmatic vagal transections. Vagotomy abolished the suppression of sham feeding by intraintestinal infusion of maltose or oleate. Suppression of sham feeding by intraintestinal L-phenylalanine was reduced but not abolished by vagotomy. The results of this examination indicate that the vagus nerve mediates suppression of the sham feeding by intraintestinal maltose and oleate but is only partially responsible for suppression of food intake produced by L-phenylalanine. Taken together with previously published data these results suggest that effects on feeding by specific nutrients may be mediated by anatomically distinct populations of visceral afferent neurons.