Collaborative Evaluations of Diagnostic Tests Experience of the Radiology Diagnostic Oncology Group
Collaborative Evaluations of Diagnostic Tests Experience of the Radiology Diagnostic Oncology Group
复制标题
放射诊断肿瘤学组诊断测试经验的协作评估
作者：
C. Gatsonis;B. McNeil
多中心协作研究提供了一种有效的方法来满足对成像技术的及时和普遍的临床评估日益增长的需求。本文讨论了协作前瞻性临床评估的研究设计、统计分析、组织和日常小组操作问题。它很大程度上借鉴了作者在放射诊断肿瘤学小组的经验，该小组是一个由国家癌症研究所资助的合作小组，该小组对诊断成像方式对各种类型癌症进行分期的能力进行比较研究，包括前列腺、肺癌、胰腺、结肠和直肠的癌症。该小组 2 1/2 年经验的结果预示着这种方法对放射学研究未来发展的重要性。
Multicenter, collaborative studies offer an effective way to meet the growing need for timely and generalizable clinical evaluations of imaging technologies. This article discusses issues of study design, statistical analysis, organization, and day-to-day group operation for collaborative prospective clinical evaluations. It draws significantly on the authors' experience with the Radiology Diagnostic Oncology Group, a cooperative group funded by the National Cancer Institute, which conducts comparative studies of the ability of diagnostic imaging modalities to enable the staging of various types of cancer including that of the prostate gland, lung, pancreas, colon, and rectum. The results from 2 1/2 years of the experience of this group hold promise for the importance of this approach to the future growth of radiologic research.