Fiber-optic conical microsensors for surface plasmon resonance using chemically etched single-mode fiber
Fiber-optic conical microsensors for surface plasmon resonance using chemically etched single-mode fiber
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DOI：
10.1016/j.aca.2004.07.045
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发表时间：
2004-10-11
影响因子：
6.2
通讯作者：
Suzuki, K
中科院分区：
文献类型：
--
作者：
Kurihara, K;Ohkawa, H;Suzuki, K
在近场扫描光学显微镜（NSOM）光纤探针制作技术的基础上，研制出一种新型表面等离子体共振（SPR）光纤微传感器。采用化学腐蚀法在锥形纤芯单模光纤上镀上一层金金属膜的方法制备了新型SPR微传感器。将其应用于微流控器件中流动透明液体折射率的实时监测。当SPR微传感器的化学修饰与自组装单层提出一个羟基，他们成功地响应于折射率从1.33至1.40 RI的灵敏度为0.008 RI单位，涵盖了有趣的区域SPR生物传感器在水溶液中操作。(C)2004 Elsevier B.V.保留所有权利。
A new type of the fiber-optic microsensor for surface plasmon resonance (SPR) was created on the basis of the fabrication technology of optical fiber probes in near-field scanning optical microscopy (NSOM). The newly developed SPR microsensors were prepared by coating a gold-metallic film on the chemically etched single mode fiber containing a conical core. They were applied to the real-time monitoring of the refractive index (RI) of transparent liquids flowing in the microfluidic device. When SPR microsensors were chemically modified with a self-assembled monolayer presenting a hydroxyl group, they successfully responded to the refractive index from 1.33 to 1.40 RI with a sensitivity of 0.008 RI units that covers the interesting regions for SPR biosensor operated in a water solution. (C) 2004 Elsevier B.V. All rights reserved.