High-resolution, multiple gradient-echo functional MRI at 1.5 T

High-resolution, multiple gradient-echo functional MRI at 1.5 T
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DOI:
10.1016/s0730-725x(98)00191-x
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发表时间:
1999-04-01
影响因子:
2.5
通讯作者:
Haacke, EM
Haacke, EM
中科院分区:
医学4区
文献类型:
--
作者:
Barth, M;Reichenbach, JR;Haacke, EM

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为了更好地显示功能磁共振成像(FMRI)实验中不同的激活源,提出了一种多梯度回波高分辨率成像方法。从30ms到205ms收集了8个回波,回波间隔为25ms。所有的回声都显示出显著的激活,但每个回声都显示出它自己的激活模式。根据这种可变性,似乎可以使用跨回声时间的模糊聚类分析来区分大血管贡献和小血管贡献。结果表明,多梯度回波数据采集方法在定位fMRI中对脑激活的各种血管贡献方面具有重要意义。(C)1999年爱思唯尔科学公司。
A multiple gradient echo, high resolution imaging method is proposed to better visualize different sources of activation in functional magnetic resonance imaging (fMRI) experiments. Eight echoes are collected from 30 ms to 205 ms with an echo spacing of 25 ms. All echoes show significant activation, but each echo reveals its own pattern of activation. From this variability, it appears that large vessel contributions can be separated from small vessel contributions using a fuzzy cluster analysis across echo times. The results demonstrate the importance of a multiple gradient echo data acquisition approach in localizing various vascular contributions to brain activation in fMRI. (C) 1999 Elsevier Science Inc.