Transcriptomic Analysis of Skin Color in Anole Lizards.
Transcriptomic Analysis of Skin Color in Anole Lizards.
复制标题
DOI：
10.1093/gbe/evab110
复制
发表时间：
2021-07-06
影响因子：
3.3
通讯作者：
Glor RE
中科院分区：
文献类型：
--
作者：
de Mello PLH;Hime PM;Glor RE
Color and color pattern are critical for animal camouflage, reproduction, and defense. Few studies, however, have attempted to identify candidate genes for color and color pattern in squamate reptiles, a colorful group with over 10,000 species. We used comparative transcriptomic analyses between white, orange, and yellow skin in a color-polymorphic species of anole lizard to 1) identify candidate color and color-pattern genes in squamates and 2) assess if squamates share an underlying genetic basis for color and color pattern variation with other vertebrates. Squamates have three types of chromatophores that determine color pattern: guanine-filled iridophores, carotenoid- or pteridine-filled xanthophores/erythrophores, and melanin-filled melanophores. We identified 13 best candidate squamate color and color-pattern genes shared with other vertebrates: six genes linked to pigment synthesis pathways, and seven genes linked to chromatophore development and maintenance. In comparisons of expression profiles between pigment-rich and white skin, pigment-rich skin upregulated the pteridine pathway as well as xanthophore/erythrophore development and maintenance genes; in comparisons between orange and yellow skin, orange skin upregulated the pteridine and carotenoid pathways as well as melanophore maintenance genes. Our results corroborate the predictions that squamates can produce similar colors using distinct color-reflecting molecules, and that both color and color-pattern genes are likely conserved across vertebrates. Furthermore, this study provides a concise list of candidate genes for future functional verification, representing a first step in determining the genetic basis of color and color pattern in anoles.
登录
查看更多内容
影响因子：
4.1
作者：
Glor, Richard E.;Laport, Robert G.
通讯作者：
Laport, Robert G.
影响因子：
7.8
作者：
BAGNARA, JT;TAYLOR, JD;HADLEY, ME
通讯作者：
HADLEY, ME
影响因子：
3.7
作者：
Costa-Silva J;Domingues D;Lopes FM
通讯作者：
Lopes FM
影响因子：
3.4
作者：
Braasch, Ingo;Schartl, Manfred;Volff, Jean-Nicolas
通讯作者：
Volff, Jean-Nicolas
影响因子：
5.8
作者：
Goeman, Jelle J.;Buehlmann, Peter
通讯作者：
Buehlmann, Peter