Trusting god and medicine: Spirituality in advanced cancer patients volunteering for clinical trials of experimental agents
Trusting god and medicine: Spirituality in advanced cancer patients volunteering for clinical trials of experimental agents
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DOI：
10.1002/pon.829
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发表时间：
2005-02-01
期刊：
影响因子：
3.6
通讯作者：
Tartaro, J
中科院分区：
文献类型：
--
作者：
Daugherty, CK;Fitchett, G;Tartaro, J
这项研究的目的是研究精神在自愿参加实验药物临床试验的晚期癌症患者中的作用。关于灵性（FACIT-Sp），生活质量（FACT-G），预后意识和决策偏好的信息来自162名自愿参加I期试验的晚期癌症患者。在多变量模型中，I期患者的灵性水平略高于156名未参与I期试验的晚期癌症患者（p < 0.001）。对于I期患者，灵性与生活质量呈正相关（斯皮尔曼rho = 0.36，p < 0.001）。灵性或宗教问题解决风格与I期患者对其预后或决策偏好的认识之间几乎没有关联。一位第一阶段的病人说，“我相信医生和上帝”，表达了这些病人愿意相信上帝和医学。版权所有（C）2004约翰威利父子有限公司。
The purpose of this study was to examine the role of spirituality in terminally ill cancer patients who volunteer for clinical trials of experimental agents. Information about spirituality (FACIT-Sp), quality of life (FACT-G), awareness of prognosis, and decision-making preferences was obtained from 162 advanced cancer patients who volunteered for phase I trials. In a multivariable model, phase I patients had slightly higher levels of spirituality (p < 0.001) than a group of 156 advanced cancer patients who were not participants in phase I trials. For the phase I patients, spirituality was positively associated with quality of life (Spearman rho = 0.36, p < 0.001). There was little association between either spirituality or religious problem-solving style and phase I patients' awareness of their prognosis or decision-making preferences. One phase I patient who said, 'I put faith in doctors and God,' expressed these patients' willingness to trust both God and medicine. Copyright (C) 2004 John Wiley Sons, Ltd.