Characteristics of depression in hemodialysis patients: symptoms, quality of life and mortality risk
Characteristics of depression in hemodialysis patients: symptoms, quality of life and mortality risk
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DOI：
10.1016/j.genhosppsych.2006.03.008
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发表时间：
2006-07-01
影响因子：
7
通讯作者：
Rollman, Bruce L.
中科院分区：
文献类型：
--
作者：
Drayer, Rebecca A.;Piraino, Beth;Rollman, Bruce L.
背景：终末期肾病患者的抑郁往往被忽视。我们采访了门诊患者在城市透析设施使用标准为基础的病例发现工具，以评估率，临床相关性和结果depress.Methods：初级保健评估精神障碍的情绪模块和9项患者健康问卷被用来评估抑郁症。我们使用肾脏疾病和生活质量简表测量健康相关的生活质量，使用Charlson合并症指数测量医学合并症。我们比较了社会人口学和临床特征和健康相关的生活质量的抑郁症和非抑郁症患者使用t检验和卡方检验，我们使用了一个考克斯回归模型来测试抑郁症和mortality.Results之间的关系：我们采访了62例患者，并遵循他们的平均29个月（范围，0.1-36）。17人（28%）患有重度或轻度抑郁症。抑郁症患者比非抑郁症患者更年轻，健康相关的生活质量更低。抑郁症可预测死亡率（HR= 4.1，95%CI = 1.5-32.2，P
Background: Depression is often underrecognized in patients with end-stage renal disease. We interviewed outpatients at an urban dialysis facility using a criterion-based case-finding instrument to assess the rates, clinical correlates and outcomes of depression.Methods: The Primary Care Evaluation of Mental Disorders Mood Module and the nine-item Patient Health Questionnaire were used to assess depression. We measured health-related quality of life using the Kidney Disease and Quality of Life Short Form, and medical comorbidities were measured using the Charlson Comorbidity Index. We compared the sociodemographic and clinical characteristics and health-related quality of life of depressed and nondepressed patients using t tests and the chi-square test, and we used a Cox regression model to test the relationship between depression and mortality.Results: We interviewed 62 patients and followed them for a mean of 29 months (range, 0.1-36). Seventeen (28%) had major or minor depression. Depressed patients were younger and had lower health-related quality of life than did nondepressed patients. Depression predicted mortality (HR= 4.1, 95% CI = 1.5-32.2, P