Decoys 'R' Us: A database of incorrect conformations to improve protein structure prediction
Decoys 'R' Us: A database of incorrect conformations to improve protein structure prediction
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DOI：
10.1110/ps.9.7.1399
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发表时间：
2000-07-01
期刊：
影响因子：
8
通讯作者：
Levitt, M
中科院分区：
文献类型：
--
作者：
Samudrala, R;Levitt, M
通过在一组计算机生成的构象（诱饵）上测试该函数，以确定它是否可以容易地区分天然样构象与非天然构象，从而大大增强了用于蛋白质结构预测的能量或评分函数的开发。我们已经创建了“诱饵R”Us，一个包含许多这样的构象集的数据库，以提供一个资源，允许评分功能得到改善。
The development of an energy or scoring function for protein structure prediction is greatly enhanced by testing the function on a set of computer-generated conformations (decoys) to determine whether it can readily distinguish native-like conformations from nonnative ones. We have created "Decoys 'R' Us," a database containing many such sets of conformations, to provide a resource that allows scoring functions to be improved.