Response by Mossavar-Rahmani and Wassertheil-Smoller to Letters Regarding Article, "Artificially Sweetened Beverages and Stroke, Coronary Heart Disease, and All-Cause Mortality in the Women's Health Initiative".
Response by Mossavar-Rahmani and Wassertheil-Smoller to Letters Regarding Article, "Artificially Sweetened Beverages and Stroke, Coronary Heart Disease, and All-Cause Mortality in the Women's Health Initiative".
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Mossavar-Rahmani 和 Wassertheil-Smoller 对有关文章“妇女健康倡议中的人工甜味饮料与中风、冠心病和全因死亡率”的信件的回应。
DOI：
10.1161/strokeaha.119.025714
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发表时间：
2019
期刊：
影响因子：
8.3
通讯作者：
Wassertheil-Smoller,Sylvia
中科院分区：
文献类型：
--
作者：
Mossavar-Rahmani,Yasmin;Wassertheil-Smoller,Sylvia
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We acknowledge that we cannot establish causality in this prospective study and that there may be residual confounding as raised by Pyrogianni et al. We clearly state these points in our article and we have controlled for confounders such as age, race, education, health risk variables (diabetes, cardiovascular disease, high cholesterol requiring pills, hypertension, body mass index) and behaviors (smoking, alcohol, physical activity and diet) in our analyses.Pyrogianni et al incorrectly state that there was no trend with dose in our model 4 analyses in Table 2. In fact, there was a statistically significant rising trend (P< 0.011) with a dose for coronary heart disease and (P< 0.007) with a dose for all-cause mortality. 1 We were surprised that Drs Khan, Malik, and Sievenpiper suggest our finding may be spurious, since Dr Malik was the first author on the article published just a month after ours that supported our findings for all-cause mortality in the analyses related to the Nurses’ Health Study. 2 That study also found a significant trend (P= 0.01). The hazards ratio, 95% CI for≥ 2 artificially sweetened beverage/day reported by Dr Malik and colleagues for the Nurses’