Laser-scanning photoacoustic microscopy with ultrasonic phased array transducer.

Laser-scanning photoacoustic microscopy with ultrasonic phased array transducer.
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DOI:
10.1364/boe.3.002694
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发表时间:
2012-11-01
影响因子:
3.4
通讯作者:
Jiao S
Jiao S
中科院分区:
医学2区
文献类型:
--
作者:
Zheng F;Zhang X;Chiu CT;Zhou BL;Shung KK;Zhang HF;Jiao S

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本文报道了超声相控阵在激光扫描光声显微镜(LS-PAM)中提高探测灵敏度和视野的最新研究进展。建立了一维超声相控阵的LS-PAM系统进行实验。该一维相控阵换能器由64个有源元件组成,总有源尺寸为3.2 mm × 2mm。并对该系统进行了幻影和小鼠耳的活体成像实验。实验结果表明,采用波束形成后的图像信号噪比(SNR)比单元件采集的图像提高了15 dB。实验结果表明,超声相控阵在眼科成像等高灵敏度应用中具有较好的应用前景。
In this paper, we report our latest progress on proving the concept that ultrasonic phased array can improve the detection sensitivity and field of view (FOV) in laser-scanning photoacoustic microscopy (LS-PAM). A LS-PAM system with a one-dimensional (1D) ultrasonic phased array was built for the experiments. The 1D phased array transducer consists of 64 active elements with an overall active dimension of 3.2 mm × 2 mm. The system was tested on imaging phantom and mouse ear in vivo. Experiments showed a 15 dB increase of the signal-to-noise ratio (SNR) when beamforming was employed compared to the images acquired with each single element. The experimental results demonstrated that ultrasonic phased array can be a better candidate for LS-PAM in high sensitivity applications like ophthalmic imaging.