Separation of pyrrolidine allylation products by diastereoselective enzymatic ester hydrolysis

Separation of pyrrolidine allylation products by diastereoselective enzymatic ester hydrolysis
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DOI:
10.1016/j.tetlet.2004.12.062
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发表时间:
2005-02-07
影响因子:
1.8
通讯作者:
Rogers-Evans, M
Rogers-Evans, M
中科院分区:
化学4区
文献类型:
--
作者:
Aggarwal, VK;Astle, CJ;Rogers-Evans, M

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多平行酶筛选已被用于确定潜在的催化剂选择性水解非对映异构体酯,然后随后应用于他们的分离放大。(C) 2004 Elsevier Ltd.版权所有。
A multi-parallel enzyme screen has been used to identify potential catalysts for the selective hydrolysis of diastereomeric esters and then subsequently applied in their separation upon scaleup. (C) 2004 Elsevier Ltd. All rights reserved.