Mucoid Pseudomonas aeruginosa. A sign of cystic fibrosis in young adults with chronic pulmonary disease?
Mucoid Pseudomonas aeruginosa. A sign of cystic fibrosis in young adults with chronic pulmonary disease?
复制标题
粘液铜绿假单胞菌。
DOI：
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发表时间：
1976
期刊：
影响因子：
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通讯作者：
C. Zierdt
中科院分区：
文献类型：
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作者：
H. Reynolds;P. di Sant’agnese;C. Zierdt
2例囊性纤维化的成年患者发病较晚，主要累及肺。囊性纤维化其他典型特征的缺失使诊断混乱。从痰培养中恢复粘液样铜绿假单胞菌有助于确定这些患者的诊断，因为这些粘液样分离物很少从没有囊性纤维化的受试者中获得。最近的研究发现，黏液分离物主要是铜绿假单胞菌的一种菌株，并记录了其在美国囊性纤维化患者中的广泛传播，指出了这种细菌和这种疾病之间有趣的流行病学关系。
Two adult patients with cystic fibrosis had late onset of symptoms with principal involvement only of the lungs. The absence of other typical features of cystic fibrosis confused the diagnosis. Recovery of mucoid Pseudomonas aeruginosa from sputum cultures helped to establish the diagnosis in these patients, because these mucoid isolates are rarely obtained from subjects who do not have cystic fibrosis. Recent findings, which have identified the mucoid isolates as predominantly a single strain of P aeruginosa and have documented its widespread carriage in the United States by patients with cystic fibrosis, point to an interesting epidemiologic relationship between this bacterium and this disease.