Development of syndrome severity scores for pediatric epilepsy.
Development of syndrome severity scores for pediatric epilepsy.
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小儿癫痫综合征严重程度评分的制定。
DOI：
10.1111/j.0013-9580.2004.53903.x
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
Perkins,SusanM
中科院分区：
文献类型：
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作者：
Dunn,DavidW;Buelow,JaniceM;Austin,JoanK;Shinnar,Shlomo;Perkins,SusanM
目的：对每种小儿癫痫综合征的严重程度进行评级有助于更全面地了解癫痫发作的严重程度。我们描述的发展癫痫综合征严重程度评分-儿童（ESSS-C）。方法：德尔菲技术被用来建立由国际抗癫痫联盟（ILAE）定义的儿童癫痫综合征的严重程度评分。要求具有癫痫专业知识的儿科神经科医生在1至10分量表上对每种综合征的严重程度进行评级，考虑：（a）对药物治疗的反应，（B）癫痫发作严重程度和（c）长期预后。在四个不同的轮中进行综合征严重程度评级。结果：18位专家参与了量表的编制，其中12位专家完成了全部4轮的问卷调查。如果平均值和中位数在0.5以内，则中位数作为综合征严重程度评分。否则，选择这两个数字中最接近模式的一个。严重程度评分较高（9或10）或严重程度评分较低（1或2）的并发症具有一致或接近一致的评级。分数在中间范围（4至8）的综合征有更广泛的ratings.Conclusions：如果进一步的研究提供实证支持的有效性，这些癫痫综合征的严重程度评分，那么ESSS-C有可能用于临床和在未来的研究中预测的治疗结果。
Purpose:A severity rating for each of the pediatric epilepsy syndromes can contribute to a more comprehensive understanding of seizure condition severity. We describe the development of the Epilepsy Syndrome Severity Scores–Child (ESSS–C).Methods:The Delphi Technique was used to establish severity scores for pediatric epileptic syndromes as defined by the International League Against Epilepsy (ILAE). Pediatric neurologists with expertise in epilepsy were asked to rate the severity of each syndrome on a scale of 1 to 10, considering: (a) response to medical treatment, (b) seizure severity, and (c) long‐term prognosis. Syndrome severity ratings took place in four different rounds. Experts provided initial scores in rounds 1 and 2.Results:Of the 18 experts who agreed to participate in the development of the scale, 12 completed all four rounds. The median served as the syndrome severity score if the mean and median agreed within 0.5. Otherwise, whichever of these two numbers was closest to the mode was selected. Syndromes that were rated with high severity scores (9 or 10) or low severity scores (1 or 2) had unanimous or near unanimous ratings. The syndromes with scores in the middle range (4 to 8) had a wider range of ratings.Conclusions:If further studies provide empirical support for the validity of these epileptic syndrome severity scores, then the ESSS‐C has potential for use both clinically and in future research in the prediction of outcomes of treatments.