Enhancement of Urinary Citrate in Oxalate Stone Formers by the Intake of Alkaline Salts

Enhancement of Urinary Citrate in Oxalate Stone Formers by the Intake of Alkaline Salts
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摄入碱性盐可增强草酸盐结石形成者尿中柠檬酸盐的含量

DOI:
10.1007/978-1-4684-8977-4_141
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发表时间:
1981
期刊:
The Journal of biological chemistry
影响因子:
--
通讯作者:
H. Dulce
H. Dulce
中科院分区:
--
文献类型:
--
作者:
M. Butz;H. Dulce

文献摘要

被引文献

相似文献

草酸盐结石形成者尿柠檬酸盐浓度和排泄减少。通过口服枸橼酸钾钠(Uralyt-UR),可使枸橼酸增加100%,钙减少40%。尿草酸盐、尿酸、镁和磷酸盐在治疗下保持不变。通过引入碱性柠檬酸盐,获得了提高草酸钙溶解度的两种加和效应。因此,建议将预防性Uralyt-UR治疗扩展至草酸盐结石形成者。
Oxalate stone formers have a decreased concentration and excretion of urinary citrate. By oral ingestion of K-Na-citrate (Uralyt-UR) a 100% increase of citrate and a 40% decrease of calcium is achieved. Urinary oxalate, uric acid, magnesium and phosphate remain unaltered under therapy. Two additive effects improving the solubility of calcium oxalate are obtained by the intake of alkaline citrate. Thus it is suggested to extend prophylactic Uralyt-UR therapy to oxalate stone formers.