Attenuated Psychosis Syndrome: Ready for DSM-5.1?
Attenuated Psychosis Syndrome: Ready for DSM-5.1?
复制标题
DOI：
10.1146/annurev-clinpsy-032813-153645
复制
发表时间：
2014-01-01
期刊：
影响因子：
--
通讯作者：
McGlashan, T. H.
中科院分区：
文献类型：
--
作者：
Fusar-Poli, P.;Carpenter, W. T.;McGlashan, T. H.
精神分裂症综合征的前驱症状特征已经描述了世纪，并且在过去二十年中的工作已经产生了基于这些特征的大量文献，以识别发展为精神障碍的风险增加的个体。有时被概念化为“风险状态”，有时被概念化为“障碍”的早期表现，这项工作是用几个相关但不同的结构进行的。在《精神疾病诊断与统计手册》（DSM-5）第五版编写的早期，人们就创建一种名为弱性精神病综合征（APS）的新疾病的提议征求了公众意见，出现了一系列问题，产生了有趣而重要的争议。在这篇综述中，这些批评进行了充分的讨论，APS的概念是explicated;有关的可靠性，有效性和治疗的数据进行了更新; APS的异质性被认为是和替代观点的结构提出了一级和二级预防和早期治疗的时间发展模式的重点。确定了未来的研究领域，并跟踪了DSM-5.1的潜在路线图。
Prodromal features of the schizophrenia syndrome have been described for a century, and work in the past two decades has produced a substantial literature based on these features to identify individuals at increased risk for developing a psychotic disorder. Sometimes conceptualized as a "risk state" and sometimes as early manifestations of a "disorder," the work has been conducted with several related but different constructs. Early in the preparation of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) public comment was sought on the proposal to create a new disorder termed attenuated psychosis syndrome (APS), and a range of issues emerged that generated interesting and important controversies. In this review, these criticisms are fully discussed, the APS concept is explicated; data relating to reliability, validity, and treatment are updated; the heterogeneity of APS is considered; and alternative views of the construct are presented with an emphasis on developmental pattern with timing for primary and secondary prevention and early treatment. Areas of future research are identified, and a potential roadmap for inclusion in DSM-5.1 is traced.