The Single-Probe: A Miniaturized Multifunctional Device for Single Cell Mass Spectrometry Analysis
The Single-Probe: A Miniaturized Multifunctional Device for Single Cell Mass Spectrometry Analysis
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DOI：
10.1021/ac5029038
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发表时间：
2014-10-07
影响因子：
7.4
通讯作者：
Yang, Zhibo
中科院分区：
文献类型：
--
作者：
Pan, Ning;Rao, Wei;Yang, Zhibo
我们开发了一种新的质谱学(MS)技术，单探针MS，能够对单个活细胞进行实时、原位的代谢组学分析。单探头是一种小型化的多功能采样和电离装置，直接与质谱仪耦合。其采样尖端小于单个真核细胞(
We have developed a new mass spectrometry (MS) technology, the Single-probe MS, capable of real-time, in situ metabolomic analysis of individual living cells. The Single-probe is a miniaturized multifunctional sampling and ionization device that is directly coupled to the mass spectrometer. With a sampling tip smaller than individual eukaryotic cells (