Through the genetic bottleneck:: O-rufipogon as a source of trait-enhancing alleles for O-sativa
Through the genetic bottleneck:: O-rufipogon as a source of trait-enhancing alleles for O-sativa
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DOI：
10.1007/s10681-006-9210-8
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发表时间：
2007-04-01
期刊：
影响因子：
1.9
通讯作者：
Ahn, Sang-Nag
中科院分区：
文献类型：
--
作者：
McCouch, Susan R.;Sweeney, Megan;Ahn, Sang-Nag
本文总结了10年来利用高级回交(AB)群体合作研究的结果，以a)确定与水稻表现改良相关的数量性状基因座(QTL)，b)克隆与感兴趣的关键QTL相关的基因。我们证明AB-QTL分析能够(1)成功地从野生种质中发现基于亲本表型的不明显的正等位基因(2)提供外来种质的育种价值的估计，(3)产生可作为基因分离的基础的近等基因系，也可作为亲本用于品种开发计划的进一步杂交(4)利用标记辅助选择(MAS)为等位基因的定向导入提供基于基因的标记。从研究水稻种群结构和进化史中获得的知识有助于阐明开发和同时保护水稻中划分良好的基因库的长期战略。
This paper summarizes results from a decade of collaborative research using advanced backcross (AB) populations to a) identify quantitative trait loci (QTL) associated with improved performance in rice and to b) clone genes underlying key QTLs of interest. We demonstrate that AB-QTL analysis is capable of (1) successfully uncovering positive alleles in wild germplasm that were not obvious based on the phenotype of the parent (2) offering an estimation of the breeding value of exotic germplasm, (3) generating near isogenic lines that can be used as the basis for gene isolation and also as parents for further crossing in a variety development program and (4) providing gene-based markers for targeted introgression of alleles using marker-assisted-selection (MAS). Knowledge gained from studies examining the population structure and evolutionary history of rice is helping to illuminate a long-term strategy for exploiting and simultaneously preserving the well-partitioned gene pools in rice.