Database resources of the National Center for Biotechnology Information

Database resources of the National Center for Biotechnology Information
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DOI:
10.1093/nar/gki062
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发表时间:
2005-01-01
影响因子:
14.9
通讯作者:
Yaschenko, E
Yaschenko, E
中科院分区:
生物学2区
文献类型:
--
作者:
Wheeler, DL;Barrett, T;Yaschenko, E

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除了维护GenBank(®)核酸序列数据库外,美国国家生物技术信息中心(NCBI)还提供数据检索系统和计算资源,用于分析GenBank中的数据以及通过NCBI网站提供的其他生物数据。NCBI的资源包括Entrez、Entrez编程工具、PubMed、PubMed Central、Entrez基因、NCBI分类学浏览器、BLAST、BLAST链接(BLink)、电子PCR、OrfFinder、Spidey、RefSeq、UniGene、HomoloGene、ProtEST、dbMHC、dbSNP、癌症染色体、Entrez基因组及相关工具、图谱浏览器、模型构建器、证据浏览器、直系同源簇(COGs)、逆转录病毒基因分型工具、HIV - 1/人类蛋白质相互作用数据库、SAGEmap、基因表达综合数据库(GEO)、人类孟德尔遗传在线(OMIM)、分子建模数据库(MMDB)、保守结构域数据库(CDD)以及保守结构域架构检索工具(CDART)。许多网络应用程序都有定制的BLAST程序实现方式,这些方式经过优化可用于搜索专门的数据集。所有资源都可通过NCBI主页http://www.ncbi.nlm.nih.gov访问。
In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data retrieval systems and computational resources for the analysis of data in GenBank and other biological data made available through NCBI's website. NCBI resources include Entrez, Entrez Programming Utilities, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Electronic PCR, OrfFinder, Spidey, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genomes and related tools, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups (COGs), Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, SAGEmap, Gene Expression Omnibus (GEO), Online Mendelian Inheritance in Man (OMIM), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD) and the Conserved Domain Architecture Retrieval Tool (CDART). Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized datasets. All of the resources can be accessed through the NCBI home page at http://www.ncbi.nim.nih.gov.