Case report: imaging features in a renal transplant patient with calcineurin inhibitor-induced pain syndrome (CIPS)

Case report: imaging features in a renal transplant patient with calcineurin inhibitor-induced pain syndrome (CIPS)
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DOI:
10.1007/s00256-013-1616-5
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发表时间:
2013-09-01
期刊:
影响因子:
2.1
通讯作者:
Bunke, Martin
Bunke, Martin
中科院分区:
医学4区
文献类型:
--
作者:
Chapin, Russell W.;Chua, Elizabeth;Bunke, Martin

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移植后远端肢体骨髓水肿综合征或钙调神经磷酸酶诱导的疼痛综合征(CIPS)通常是一种自限性但使人衰弱的急性疼痛综合征,已在2- 14%的肾移植受者中报告。在接受钙调磷酸酶抑制剂环孢霉素和他克莫司的患者中,该疾病在移植文献中被广泛描述。我们报告一例肾移植术后73天发生CIPS的病例,回顾影像学表现,并讨论病因和鉴别诊断。据作者所知,CIPS在放射学文献中尚未被描述为一个独特的实体。
Post-transplant distal limb bone marrow edema syndrome or calcineurin inhibitor-induced pain syndrome (CIPS) is generally a self-limiting but debilitating acute pain syndrome that has been reported in 2-14 % of renal transplant recipients. The disease is extensively described in the transplant literature in patients receiving the calcineurin inhibitors cyclosporine and tacrolimus. We present a case of CIPS arising in a patient 73 days after renal allograft, review the imaging findings, and discuss proposed etiologies and differential diagnoses. To the authors' knowledge, CIPS has not been characterized as a distinct entity in the radiology literature.