Neurostructural correlates of hope: dispositional hope mediates the impact of the SMA gray matter volume on subjective well-being in late adolescence
Neurostructural correlates of hope: dispositional hope mediates the impact of the SMA gray matter volume on subjective well-being in late adolescence
复制标题
希望的神经结构相关性：性格希望介导 SMA 灰质体积对青春期后期主观幸福感的影响
DOI：
10.1093/scan/nsaa046
复制
发表时间：
2020-04-01
影响因子：
4.2
通讯作者：
Gong, Qiyong
中科院分区：
文献类型：
--
作者：
Wang, Song;Zhao, Yajun;Gong, Qiyong
在过去的二十年中，在识别积极心理学领域的主观幸福感方面，人们一直在越来越兴趣。倾向的希望反映了一个人的目标趋势，包括途径思维（计划实现目标）和代理思维（目标定向的决心），已成为主观幸福感的稳定预测指标。然而，处置希望的神经生物学底物和预测主观幸福感的脑培养机制尚不清楚。在这里，我们通过基于结构磁共振成像的基于体素的形态计量法估算了同一等级的231名高中毕业生的这些问题。全脑回归分析和预测分析表明，较高的处置希望与左补充运动区域（SMA）的GMV稳定相关。此外，调解分析表明，处置希望介导了左SMA体积与主观幸福感之间的关系。至关重要的是，我们的结果是在调整年龄，性别，家庭社会经济状况和总GMV后获得的。总的来说，我们的研究提供了倾向希望的神经解剖学基础的新证据，并提出了处置希望对脑灰质结构与主观幸福感之间联系的潜在间接影响。
There has been increasing interest in identifying factors to predict subjective well-being in the emerging field of positive psychology over the past two decades. Dispositional hope, which reflects one's goal-directed tendencies, including both pathway thinking (planning to meet goals) and agency thinking (goal-directed determination), has emerged as a stable predictor for subjective well-being. However, the neurobiological substrates of dispositional hope and the brain-hope mechanism for predicting subjective well-being remain unclear. Here, we examined these issues in 231 high school graduates within the same grade by estimating cortical gray matter volume (GMV) utilizing a voxel-based morphometry method based on structural magnetic resonance imaging. Whole-brain regression analyses and prediction analyses showed that higher dispositional hope was stably associated with greater GMV in the left supplementary motor area (SMA). Furthermore, mediation analyses revealed that dispositional hope mediated the relation between left SMA volume and subjective well-being. Critically, our results were obtained after adjusting for age, sex, family socioeconomic status and total GMV. Altogether, our study presents novel evidence for the neuroanatomical basis of dispositional hope and suggests an underlying indirect effect of dispositional hope on the link between brain gray matter structure and subjective well-being.