BENIGN EPILEPTIFORM TRANSIENTS OF SLEEP - CLARIFICATION OF SMALL SHARP SPIKE CONTROVERSY

BENIGN EPILEPTIFORM TRANSIENTS OF SLEEP - CLARIFICATION OF SMALL SHARP SPIKE CONTROVERSY
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DOI:
10.1212/wnl.27.11.1061
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发表时间:
1977-01-01
期刊:
影响因子:
9.9
通讯作者:
PEDLEY, TA
PEDLEY, TA
中科院分区:
医学1区
文献类型:
--
作者:
WHITE, JC;LANGSTON, JW;PEDLEY, TA

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对120名被剥夺睡眠24小时的正常人进行脑电图检查。在志愿者中,24%的人在非快速眼动睡眠的第1或第2阶段表现出一次或多次癫痫样瞬变。这些电位通常表现为单相或双相尖峰,不伴有尖锐波或局灶慢化。当它们丰富时,它们零星地、独立地发生在两个半球,但在前腹膜颞区发育最好。在相同条件下记录的599例连续转诊患者中发现20%的类似尖峰发生率。显然,这些癫痫样的睡眠瞬间,称为小尖峰,是正常的,在评估癫痫发作患者时没有诊断价值。
EEG were performed on 120 normal subjects sleep deprived for 24 h. Of the volunteers, 24% exhibited 1 or more epileptiform transients during stages 1 or 2 of non-rapid eye movement sleep. These potentials usually appeared as monophasic or diphasic spikes unaccompanied by sharp waves or focal slowing. When abundant, they occurred sporadically and independently over both hemispheres, but were best developed in the anteromesial temporal regions. A 20% incidence of similar spikes was found in 599 consecutively referred patients recorded under the same conditions. Apparently these epileptiform transients of sleep, called small sharp spikes, are normal of no diagnostic value in the evaluation of patients with seizures.