Photoinduced drug release from complexes of liposome and fluorescent silver nanoparticles
Photoinduced drug release from complexes of liposome and fluorescent silver nanoparticles
复制标题
脂质体和荧光银纳米颗粒复合物的光诱导药物释放
DOI：
10.1039/c3ra48082h
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
安学勤
中科院分区：
文献类型：
--
作者：
李烈列;安学勤
将荧光银纳米粒子（AgNPs）包埋在脂质体双层中，作为光热开关，实现光诱导药物释放。银纳米粒子在脂质体中可以吸收光能，将光能转化为局部热，诱导脂质体相变，释放药物。药物从银纳米粒子脂质体中的释放可以通过照射时间和银纳米粒子浓度来控制。
Fluorescent silver nanoparticles (AgNPs) were embedded in the bilayer of liposomes and acted as a photothermic switch for photoinduced drug release. AgNPs in the liposome could absorb light energy, convert optical energy into localized heat, induce phase transition of liposome and release drug. The drug released from the AgNPs–liposome could be controlled by the irradiation time and AgNPs concentration.