Symptoms of generalized anxiety disorder as a risk factor for substance use among adults living with HIV.

Symptoms of generalized anxiety disorder as a risk factor for substance use among adults living with HIV.
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DOI:
10.1080/09540121.2020.1808163
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发表时间:
2021-05
期刊:
影响因子:
1.7
通讯作者:
Ennis N
Ennis N
中科院分区:
医学4区
文献类型:
--
作者:
Mannes ZL;Dunne EM;Ferguson EG;Cook RL;Ennis N

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这项研究调查了佛罗里达州 932 名艾滋病毒感染者 (PLWH) 的广泛性焦虑症 (GAD) 症状与药物滥用之间的关联。 PLWH 完成了一份 45 分钟的调查问卷,评估人口统计、广泛性焦虑症和抑郁症症状,以及酒精、香烟、大麻、快克/可卡因和注射毒品等物质的使用情况。 GAD-7 测量了焦虑症状,并将参与者分为无/轻度焦虑(得分 0-9)或中度/重度症状(得分≥10)。调整后的二元逻辑回归评估了中重度广泛性焦虑症症状与物质使用之间的关联,同时控制了包括抑郁症状在内的协变量。大约三分之一 (31.4%) 的样本报告患有中度/重度广泛性焦虑症 (GAD) 症状。控制协变量后,具有中度/重度广泛性焦虑症症状的感染者报告当前吸烟情况(AOR=1.70,95% CI=1.18-2.45 p=0.004)、过去 30 天危险饮酒情况(AOR=1.50,95% CI=1.04-2.16,p=0.028)和过去 12 个月的可能性更大与报告无/轻微症状的感染者相比,非注射快克/可卡因使用(AOR=1.75,95% CI=1.13-2.69,p=0.011)。研究结果表明,中度/重度广泛性焦虑症症状在佛罗里达州的艾滋病病毒感染者样本中很常见,并且与吸烟、强效快克/可卡因和有害饮酒有关。未来的研究应探索减少共病焦虑和药物滥用的干预措施。
This study examined the association between symptoms of generalized anxiety disorder (GAD) and substance use among 932 people living with HIV (PLWH) in Florida. PLWH completed a 45-minute questionnaire assessing demographics, symptoms of GAD and depression, and use of substances including alcohol, cigarettes, marijuana, crack/cocaine, and injection drugs. The GAD-7 measured symptoms of anxiety and participants were categorized as experiencing none/mild anxiety (score 0-9) or moderate/severe symptoms (score ≥10). Adjusted binary logistic regressions assessed the association between moderate-severe GAD symptoms and substance use while controlling for covariates, including depressive symptoms. Approximately one-third (31.4%) of the sample reported experiencing moderate/severe symptoms of GAD. After controlling for covariates, PLWH with moderate/severe symptoms of GAD had greater odds of reporting current cigarette use (AOR=1.70, 95% CI=1.18-2.45 p=0.004), past 30-day hazardous alcohol consumption (AOR=1.50, 95% CI=1.04-2.16, p=0.028), and past 12-month non-injection crack/cocaine use (AOR=1.75, 95% CI=1.13-2.69, p=0.011) compared to PLWH reporting none/mild symptoms. Findings demonstrate that moderate/severe GAD symptoms were common among this sample of PLWH in Florida and were associated with use of cigarettes, crack/cocaine, and hazardous alcohol consumption. Future studies should explore interventions to reduce comorbid anxiety and substance use.
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