Courtship behavior induced by appetitive olfactory memory.
Courtship behavior induced by appetitive olfactory memory.
复制标题
由食欲嗅觉记忆诱发的求爱行为。
DOI：
10.1080/01677063.2019.1593978
复制
发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Yamagata N.
中科院分区：
文献类型：
--
作者：
Onodera Y;Ichikawa R;Terao K;Tanimoto H;Yamagata N.
食物奖励和有害惩罚等强化信号可以改变不同的行为。这对于果蝇（Drosophila melanogaster）来说也是如此，它可以通过气味和糖奖励或电击惩罚来调节。尽管学习调节了各种各样的行为，但传统上，条件反应是通过选择中改变的气味偏好来测量的，而其他记忆引导的行为却很少被研究。在这里，我们通过采用视频记录和半自动处理流程，分析了果蝇在糖联想学习后的详细条件气味反应。轨迹分析显示，多种行为成分随着对奖励气味的条件性处理而改变。值得注意的是，我们发现侧翼伸展是D. 求偶行为的标志。黑腹果蝇，特别是在奖励气味存在的情况下显着增加。引人注目的是，蘑菇体输出的基因破坏并没有损害条件求爱的增加，同时显着削弱了条件气味的接近。我们的结果强调了条件反应的复杂性及其独特的调节机制，这些机制可能是果蝇协调但复杂的记忆引导行为的基础。
Reinforcement signals such as food reward and noxious punishment can change diverse behaviors. This holds true in fruit flies,Drosophila melanogaster, which can be conditioned by an odor and sugar reward or electric shock punishment. Despite a wide variety of behavior modulated by learning, conditioned responses have been traditionally measured by altered odor preference in a choice, and other memory-guided behaviors have been only scarcely investigated. Here, we analyzed detailed conditioned odor responses of flies after sugar associative learning by employing a video recording and semi-automated processing pipeline. Trajectory analyses revealed that multiple behavioral components were altered along with conditioned approach to the rewarded odor. Notably, we found that lateral wing extension, a hallmark of courtship behavior ofD. melanogaster, was robustly increased specifically in the presence of the rewarded odor. Strikingly, genetic disruption of the mushroom body output did not impair conditioned courtship increase, while markedly weakening conditioned odor approach. Our results highlight the complexity of conditioned responses and their distinct regulatory mechanisms that may underlie coordinated yet complex memory-guided behaviors in flies.