Cross-calibration of fat and lean measurements by dual-energy X-ray absorptiometry to pig carcass analysis in the pediatric body weight range

Cross-calibration of fat and lean measurements by dual-energy X-ray absorptiometry to pig carcass analysis in the pediatric body weight range
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DOI:
10.1093/ajcn/63.3.293
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发表时间:
1996-03-01
影响因子:
7.1
通讯作者:
Goran, MI
Goran, MI
中科院分区:
医学1区
文献类型:
--
作者:
Pintauro, SJ;Nagy, TR;Goran, MI

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本研究的目的是用双能X射线吸收测量仪(DXA)对儿童体重范围内的猪身体进行化学分析,以交叉校准身体成分的测量。18头猪(体重25.5+/-7.0 kg;体脂9.9-32.8%)在儿童中等扫描模式和成人II级快速细节扫描模式下,用LUNAR DPX-L密度计进行二次扫描。然后将猪宰杀,并对它们的身体进行完整的分析。在两种扫描模式下,屠体、瘦肉和脂肪含量与DXA测量高度相关(Pearson r值和GT;0.98)。对于瘦体重,屠体含量与DXA测量之间的关系与成人模式下的同一性没有显著差异,但在儿科模式下。对于脂肪质量,在成人和儿童模式中,屠体含量和DXA测量之间的关系与身份线显著不同。在重复扫描中,DXA测量瘦质量和脂肪质量的可靠性在两种扫描模式下都很好。由于成人和儿童扫描模式都不能提供准确的脂肪和瘦肉量测量,我们推导了特定的修正系数来改进总脂肪和瘦肉室的测量,从而将LUNAR DPX-L校准到实验室猪的屠体分析标准。
The objective of this study was to cross-calibrate measurements of body composition by dual-energy X-ray absorptiometry (DXA) with chemical analysis of carcasses of pigs in the pediatric range of body weight. Eighteen pigs (25.5 +/- 7.0 kg; 9.9-32.8% body fat) were scanned in duplicate by using DXA with a Lunar DPX-L densitometer in the pediatric medium and ii adult fast-detail scan modes. Pigs were then killed and their carcasses analyzed completely. Carcass lean and fat contents were highly correlated with DXA measurements in both scan modes (Pearson r values > 0.98). For lean mass, the relation between carcass content and DXA measures was not significantly different from the line of identity in the adult mode, but was in the pediatric mode. For fat mass, the relations between carcass content and DXA measures were significantly different from the Line of identity in both the adult and pediatric modes. In duplicate scans, the reliability of DXA measures of lean mass and fat mass was excellent in both scan modes. Because neither the adult nor the pediatric scan mode provided accurate measures of fat and lean mass, we derived specific correction factors to improve the measurement of total fat and lean compartments, thereby calibrating the Lunar DPX-L to the laboratory standard of carcass analysis in pigs.