Cognitive function in people with chronic illness: Inflammatory bowel disease and Irritable Bowel Syndrome
Cognitive function in people with chronic illness: Inflammatory bowel disease and Irritable Bowel Syndrome
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DOI：
10.1207/s15324826an1002_05
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发表时间：
2003-01-01
影响因子：
--
通讯作者：
Wilson, C
中科院分区：
文献类型：
--
作者：
Attree, EA;Dancey, CP;Wilson, C
最近的研究表明，患有慢性疾病的人经常会出现认知缺陷，这种缺陷可能是特定类型的疾病所特有的，反映了疾病本身的过程，或者它们可能是许多慢性疾病的共同缺陷。我们的研究调查了器质性疾病（炎症性肠病）患者是否表现出相对于对照组和功能性疾病（肠易激综合征）患者的认知功能障碍，如果是这样，阐明这种功能障碍发生的机制。一个准实验设计使用三组参与者提供智商，记忆力和认知灵活性的分数。绝对分数的差异很小。然而，在小组和智商之间发现了一个明显的相互作用效应：与他们自己的表现智商和对照组的语言智商相比，疾病组表现出语言智商的缺陷。这种语言缺陷不能用抑郁、认知负荷或药物来解释。
Recent research has shown that people with chronic illnesses often experience cognitive deficits, such deficits may be specific to a particular type of illness, reflecting the disease process itself, or they may be deficits that are common across a number of chronic illnesses. Our study investigated whether people with an organic disease (Inflammatory Bowel Disease) show cognitive dysfunction relative to the control group and people with a functional illness (Irritable Bowel Syndrome), and if so, to elucidate the mechanisms by which such dysfunction occurs. A quasi-experimental design using three groups of participants provided scores on IQ, memory, and cognitive flexibility. Differences in absolute scores were slight. However, a noticeable interaction effect was found between group and IQ: The illness groups showed a deficit in verbal IQ relative to both their own performance IQ and to that of the control group verbal IQ. This verbal deficit cannot be explained by depression, cognitive load, or medication.