Improved performance of Gen-Probe amplified Mycobacterium tuberculosis direct test when 500 instead of 50 microliters of decontaminated sediment is used

Improved performance of Gen-Probe amplified Mycobacterium tuberculosis direct test when 500 instead of 50 microliters of decontaminated sediment is used
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DOI:
10.1128/jcm.34.1.222-223.1996
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发表时间:
1996-01-01
影响因子:
9.4
通讯作者:
Matter, L
Matter, L
中科院分区:
医学2区
文献类型:
--
作者:
Bodmer, T;Mockl, E;Matter, L

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使用Gen-Probe的扩增结核分枝杆菌直接试验(amplification Mycobacterium Tuberculosis Direct Test)对717例呼吸道标本分别使用500 μ l沉淀物进行筛选,与我们之前使用50 μ l沉淀物(71.4%)的研究相比,该试验的灵敏度(83.3%)有所提高,但对其特异性(分别为99.4%和99.0%)没有不良影响。
Using 500 mu l of sediment each for screening of 717 respiratory tract specimens by Gen-Probe's Amplified Mycobacterium Tuberculosis Direct Test improved the sensitivity (83.3%) of the assay, compared,vith our previous study using 50 mu l of sediment (71.4%), without adversely affecting its specificity (99.4 and 99.0%, respectively).