Agreement between continuous cardiac output measured by the fourth-generation FloTrac/Vigileo system and a pulmonary artery catheter in adult liver transplantation.

Agreement between continuous cardiac output measured by the fourth-generation FloTrac/Vigileo system and a pulmonary artery catheter in adult liver transplantation.
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成人肝移植中第四代FloTrac/Vigileo系统和肺动脉导管测量的连续心输出量之间的一致性

DOI:
10.1038/s41598-022-14988-z
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发表时间:
2022-07-01
期刊:
影响因子:
4.6
通讯作者:
Kawamoto, Shuji
Kawamoto, Shuji
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Murata, Yutaka;Imai, Takumi;Takeda, Chikashi;Mizota, Toshiyuki;Kawamoto, Shuji

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在终末期肝功能衰竭的肝移植中,由于血流动力学不稳定,连续心输出量(CCO)监测用于循环管理。CCO通常使用微创FloTrac/Vigileo系统(FVS-CCO)而不是高度侵入性肺动脉导管(PAC-CCO)进行测量。由于更新了心输出量算法,FVS的准确性有所提高,但这种变化对肝移植中FVS-CCO准确性的影响尚不清楚。在本研究中,我们评估了2019年9月至2021年6月在京都大学医院接受计划或紧急肝移植的20例年龄≥ 20岁患者中第四代FVS-CCO和PAC-CCO之间的一致性。在手术前获得同意书,并在整个手术期间记录数据。对提取的数据进行Pearson相关系数(r)、Bland-Altman和4象限图分析。共获得1517个PAC-CCO与FVS-CCO数据对。平均PAC-CCO为8.73 L/min,平均体循环血管阻力为617.5 dyne·s·cm-5,r为0.48,偏倚为1.62 L/min,95%一致性限值为-3.04至6.27,百分比误差为54.36%。这些结果表明,在成人肝移植受者中,第四代FVS-CCO和PAC-CCO之间的一致性和趋势较低。
In liver transplantation for end-stage liver failure, monitoring of continuous cardiac output (CCO) is used for circulatory management due to hemodynamic instability. CCO is often measured using the minimally invasive FloTrac/Vigileo system (FVS-CCO), instead of a highly invasive pulmonary artery catheter (PAC-CCO). The FVS has improved accuracy due to an updated cardiac output algorithm, but the effect of this change on the accuracy of FVS-CCO in liver transplantation is unclear. In this study, we assessed agreement between fourth-generation FVS-CCO and PAC-CCO in 20 patients aged ≥ 20 years who underwent scheduled or emergency liver transplantation at Kyoto University Hospital from September 2019 to June 2021. Consent was obtained before surgery and data were recorded throughout the surgical period. Pearson correlation coefficient (r), Bland–Altman and 4-quadrant plot analyses were performed on the extracted data. A total of 1517 PAC-CCO vs. FVS-CCO data pairs were obtained. The mean PAC-CCO was 8.73 L/min and the mean systemic vascular resistance was 617.5 dyne·s·cm-5, r was 0.48, bias was 1.62 L/min, the 95% limits of agreement were − 3.04 to 6.27, and the percentage error was 54.36%. These results show that agreement and trending between fourth-generation FVS-CCO and PAC-CCO are low in adult liver transplant recipients.
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