Rasch Analysis of the Ocular Surface Disease Index (OSDI)

Rasch Analysis of the Ocular Surface Disease Index (OSDI)
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DOI:
10.1167/iovs.11-8027
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发表时间:
2011-11-01
影响因子:
4.4
通讯作者:
Nichols, Kelly K.
Nichols, Kelly K.
中科院分区:
医学2区
文献类型:
--
作者:
Dougherty, Bradley E.;Nichols, Jason J.;Nichols, Kelly K.

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目的。眼表疾病指数(OSDI)是一个由12个项目组成的量表,用于评估与干眼病相关的症状及其对视力的影响。它的信度和效度已经在经典测试理论框架内进行了研究,并在最近使用了Rasch分析。本研究的目的是更全面地调查其反应类别结构的功能,其三个子量表的效度,以及潜在结构的单维度。方法:分析了172名参与绝经后干眼研究(DEIM)的女性对OSDI的反应,她们以前被诊断为干眼或报告有明显的眼刺激和干燥。对反应类别结构和项目匹配统计进行评估,以评估模型匹配。采用人员分离统计法检验各分量表的效度。结果所推荐的五类反应结构导致反应阈值紊乱。四个类别的结构导致了有序的阈值。所有12个项目的项目流入统计都是可以接受的。这种类别结构的人称分离较好,人称分离指数为2.16。三个分量表都没有显示出足够的人与人之间的距离。主成分分析显示了另一个显著的因素,三个环境项目的负荷显著。结论:在折叠类别以排序反应阈值后,所有项目都表现出可接受的符合模型。原来的分量表没有被证明是有效的,而且有一些证据表明多维和针对性差。(投资眼科VS科学。2011年;52:8630-8635)doi:10.1167/iovs.11-8027
PURPOSE. The Ocular Surface Disease Index (OSDI) is a 12-item scale for the assessment of symptoms related to dry eye disease and their effect on vision. Its reliability and validity have been investigated within the classical test theory framework and, more recently, using Rasch analysis. The purpose of the present analysis was to more completely investigate the functioning of its response category structure, the validity of its three subscales, and the unidimensionality of the latent construct it is intended to assess.METHODS. Responses to the OSDI from 172 females participating in the Dry Eye in Postmenopause (DEiM) study who had previously been diagnosed with dry eye or reported significant ocular irritation and dryness were analyzed. Response category structure and item fit statistics were evaluated for assessment of model fit. Person separation statistics were used to examine the validity of the subscales. Unidimensionality was assessed by principal component analysis (PCA) of model residuals.RESULTS. The recommended five-category response structure resulted in disordered response thresholds. A four-category structure resulted in ordered thresholds. Item infit statistics were acceptable for all 12 items. Person separation with this category structure was adequate, with a person separation index of 2.16. None of the three subscales demonstrated adequate person separation. PCA showed one other significant factor onto which the three environmental items loaded significantly.CONCLUSIONS. All items demonstrated acceptable fit to the model after collapsing categories to order the response thresholds. The original subscales did not prove valid, and there is some evidence of multidimensionality and poor targeting. (Invest Ophthalmol Vis Sci. 2011;52:8630-8635) DOI: 10.1167/iovs.11-8027