Raw hamburger: an interstate common source of human salmonellosis.
Raw hamburger: an interstate common source of human salmonellosis.
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生汉堡：人类沙门氏菌病的州际常见来源。
DOI：
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发表时间：
1978
影响因子：
5
通讯作者：
D. L. Decker
中科院分区：
文献类型：
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作者：
R. Fontaine;S. Arnon;W. Martin;T. Vernon;E. Gangarosa;J. J. Farmer;A. B. Moran;J. H. Silliker;D. L. Decker
1975年9月和10月，美国首次发现了沙门氏菌病的州际共源爆发，当时科罗拉多卫生部通过常规沙门氏菌监测注意到纽波特沙门氏菌分离株增加了10倍。在一项病例对照研究中评估了18例具有独特抗生素耐药模式（四环素，链霉素和磺胺类药物）的原发病例，发现疾病与食用一家杂货连锁店的任何商店的生汉堡包（p <0.001）有关（p <0.001）。得克萨斯州达拉斯的一家加工厂供应科罗拉多市场，也供应其他州，这些其他州被警告。马里兰州发现了9个S.与科罗拉多暴发一样，纽波特分离株具有相同的克氏菌，患病与食用来自同一杂货连锁店的生牛肉或非常罕见的碎牛肉有关（p <0.03）。第三次爆发S.纽波特与同样的爆炸发生在佛罗里达的一个军事基地。S.从科罗拉多和佛罗里达回收的冷冻汉堡包中培养出了与人类流行病分离株具有相同菌群和噬菌体裂解模式的纽波特。相关的汉堡包起源于同一个达拉斯，得克萨斯州，加工厂。尚未确定流行菌株的来源，但该生物体可能在交付给工厂之前就已产生。
An interstate common-source outbreak of salmonellosis was first detected in the United States in September and October, 1975, when a tenfold increase in Salmonella newport isolates was noted through routine salmonella surveillance by the Colorado Department of Health. Eighteen primary cases with a distinctive antibiotic resistance pattern (tetracycline, streptomycin, and sulfonamides) were evaluated in a case-control study, and illness was found to be associated with eating raw hamburger (p less than .001) from any store of one grocery chain (p less than .001). A Dallas, Texas, processing plant that supplied the Colorado markets also supplied other states, and these other states were alerted. Maryland discovered nine S. newport isolates with the same antibiogram and, as in the Colorado outbreak, illness was associated with eating raw or very rare ground beef from the same grocery chain (p less than .03). A third outbreak of S. newport with the same antibiogram occurred on a Florida military base. S. newport with the same antibiogram and a phage lysis pattern identical to those of the human epidemic isolates was cultured from frozen hamburger recovered in Colorado and Florida. The associated hamburger originated at the same Dallas, Texas, processing plant. A source of the epidemic strain was not identified, but the organism probably originated before delivery to the plant.