Highly efficient construction of large molecular cavity using 1,3-alternate tetraoxacalix[2]arene[2]triazine as a platform.
Highly efficient construction of large molecular cavity using 1,3-alternate tetraoxacalix[2]arene[2]triazine as a platform.
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DOI：
10.1039/b805293j
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发表时间：
2008-08
影响因子：
4.9
通讯作者：
Bao-Yong Hou;Qi-Yu Zheng;De‐Xian Wang;Zhi-tang Huang;Mei-Xiang Wang
中科院分区：
文献类型：
--
作者：
Bao-Yong Hou;Qi-Yu Zheng;De‐Xian Wang;Zhi-tang Huang;Mei-Xiang Wang
在K2 CO 3存在下，在THF中，由氰尿酸酰氯和1，3-二羟基苯甲酸苄酯合成的大环化合物二氯取代四氧杂杯[2]芳烃[2]三嗪与不同几何构型的双亲核试剂发生了高效的亲核取代反应，以2+2的方式制备大的和尺寸可调的腔双-四氧杂杯[2]芳烃[2]三嗪。
In the presence of K(2)CO(3) in refluxing THF, dichloro-substituted tetraoxacalix[2]arene[2]triazine, a readily available macrocyclic compound from cyanuric acid chloride and benzyl 1,3-dihydroxybenzoate, underwent highly efficient nucleophilic displacement reactions with bis-nucleophilic reagents of different geometry, length and chirality in a 2+2 fashion to produce large and size-tunable cavity bis-tetraoxacalix[2]arene[2]triazines in good to excellent yields.