c-Maf: The magic wand that turns on LSEC fate.
c-Maf: The magic wand that turns on LSEC fate.
复制标题
c-Maf:开启 LSEC 命运的魔杖。
DOI:
10.1016/j.stem.2022.03.011
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发表时间:
2022
期刊:
影响因子:
23.9
通讯作者:
Gouon-Evans,Valerie
中科院分区:
文献类型:
--
作者:
Smith,AnnaR;Gouon-Evans,Valerie
In this issue ofCell Stem Cell, Gómez-Salinero et al. (2022) identify c-Maf as a driver for murine liver sinusoidal endothelial cell (LSEC) fate and function during liver development, homeostasis, and repair. Similarly, c-Maf defines human LSECs, and its overexpression specializes generic HUVECs into functional induced-LSECs, potentiating regenerative therapeutics.