Commissioning and Comprehensive Quality Assurance of commercial 3D Treatment Planning System using IAEA Technical Report Series-430
Commissioning and Comprehensive Quality Assurance of commercial 3D Treatment Planning System using IAEA Technical Report Series-430
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DOI：
10.1007/bf03179346
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发表时间：
2008-09-01
影响因子：
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通讯作者：
Deshpande, D. D.
中科院分区：
文献类型：
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作者：
Jamema, S. V.;Upreti, R. R.;Deshpande, D. D.
这项工作的目的是报告调试结果，并建立一个质量保证（QA）计划的商业三维治疗计划系统（TPS）的基础上，原子能机构技术报告系列430。Eclipse（TM）v 7.3.10，（Varian Medical Systems，Palo Alto，CA，USA）TPS用于Clinac 6 EX（Varian Medical Systems，Palo Alto，CA，USA）直线加速器。采集了具有各种已知不均匀性的体模的CT图像。将图像传输到TPS，并测试与患者数据采集、解剖建模、计划评价和剂量计算相关的各种参数。剂量学参数，包括开放，不对称和楔形字段，斜入射，建立区域的行为和SSD的依赖进行了评价。对代表性临床病例进行MU计算和点剂量测试。测量值与已知CT值之间的最大变化为20 +/- 11.7 HU（1 SD）。发现所有非剂量测定试验的结果均在公差范围内，但发现尖角处的膨胀变形。DVH计算的准确性取决于网格大小。TPS计算的所有剂量学参数与测量值吻合良好，但对于不对称的开放和楔形野，发现几个点超出公差。较小的网格尺寸计算显示在积聚区的剂量计算更好的一致性。MU计算的独立测试显示变化在+/- 2%内（相对于计划系统），同时当中心轴被阻断时观察到3.0%的变化。测试结果与IAEA TRS 430规定的公差一致。调试测试的子集已被确定为正在进行的QA计划的基线数据。
The purpose of this work is to report the results of commissioning and to establish a quality assurance (QA) program for commercial 3D treatment planning system (TPS) based on IAEA Technical Report Series 430. Eclipse (TM) v 7.3.10, (Varian Medical Systems, Palo Alto, CA, USA) TPS was commissioned for a Clinac 6EX (Varian Medical Systems, Palo Alto, CA, USA) linear accelerator. CT images of a phantom with various known in-homogeneities were acquired. The images were transferred to TPS and tested for various parameters related to patient data acquisition, anatomical modeling, plan evaluation and dose calculation. Dosimetric parameters including open, asymmetric and wedged shaped fields, oblique incidence, buildup region behavior and SSD dependence were evaluated. Representative clinical cases were tested for MU calculation and point doses. The maximum variation between the measured and the known CT numbers was 20 +/- 11.7 HU (1 SD). The results of all non-dosimetric tests were found within tolerance, however expansion at the sharp corners was found distorted. The accuracy of the DVH calculations depends on the grid size. TPS calculations of all the dosimetric parameters were in good agreement with the measured values, however for asymmetric open and wedged fields, few points were found out of tolerance. Smaller grid size calculation showed better agreement of dose calculation in the build-up region. Independent tests for MU calculation showed a variation within +/- 2% (relative to planning system), meanwhile variation of 3.0% was observed when the central axis was blocked. The test results were in agreement with the tolerance specified by IAEA TRS 430. A subset of the commissioning tests has been identified as a baseline data for an ongoing QA program.