Three-Dimensional Reconstruction of in vivo Human White Matter Tracts
Three-Dimensional Reconstruction of in vivo Human White Matter Tracts
复制标题
体内人体白质束的三维重建
DOI：
--
复制
发表时间：
2000
期刊：
影响因子：
--
通讯作者：
M. Solaiyappan
中科院分区：
文献类型：
--
作者：
S. Moril;M. Solaiyappan
r~~~~~~~~/sinf~~~~riolr腰束束，钩侧额枕束)，内部和外部原因（包括外部辐射，皮质-脊髓/神经球束和丘脑前辐射）和边缘系统。将结果与最佳可用组织学知识进行比较，以验证该技术。这些测量在三名健康志愿者中重复了三次以上，并研究了个体内部的可还原性。此外，还将讨论纤维重建技术的发展和最佳DTI方案，以改善临床情况下成像分辨率和扫描时间的限制。所有研究均使用1.5 T Philips Gyroscan NT系统进行。DTI成像采用多层分段EPI进行心脏门控和导航回波相位校正。每个激励采用15回声采集得到128 × 95的数据矩阵。切片厚度1.5-3.2 mm，无间隙。DTI采用6个独立的梯度方向组合进行。将多个扩散加权图像的每个像素处的强度拟合到L中，得到三个特征值和特征向量。超过12个记录良好的专业；白质束从解剖标志中被识别出来。使用FACT方法进行跟踪4。重建结果为组织学知识。与个体内可重复性研究相比，DTI研究在三个正常受试者中重复了三次以上，并且图像被共同注册。在不同测量值的相同位置选择跟踪种子像素，并测量跟踪轨迹的偏差。
r~~~~~~~~/sinf~~~~riolrOngltudlnal fasciculi, uncinate fronto-occipital fasciculus), internal and external causules (including outic radiations, cortico-spinal/cbrticobulbar tract, and anterior thalamic radiation), and limbic systems. The results were compared to the best available histological knowledge to validate the technique. The measurements were repeated more than three times for three healthy volunteers and intraindividual re reducibility f was investigated. In addition, detar s of fiber reconstruction techniques and optimal DTI protocols to ameliorate limitations in the imaging resolution and scanning time in clinical situation will be discussed. Methods and Materials All studies were performed using a 1.5 T Philips Gyroscan NT system. DTI imaging was performed using multislice segmented EPI with cardiac gating and navigator echo phase correction. A data matrix of 128 x 95 was obtained using 15-echo acquisition per every excitation. Slice thickness was 1.5-3.2 mm without gaps. DTI was performed using 6 independent combinations of gradient directions. Intensities at each nixel of multinle diffusionweighted images were fitted to L obtain three eigenvalues and eigenvectors. More than 12 welldocumented majo; white matter tracts were identified from anatomical landmarks. Tracking was performed using the FACT method4. The reconstruction results were then histological knowledge. For compared to intra-individual reproducibility studies, DTI studies were repeated more than three times for three normal subjects and images were co-registered. Seed pixels for tracking were chosen in identical locations among the different measurements and deviations in the tracking trajectories were measured.