Amplification of the sylvatic cycle of dengue virus type 2, Senegal, 1999-2000: Entomologic findings and epidemiologic considerations
Amplification of the sylvatic cycle of dengue virus type 2, Senegal, 1999-2000: Entomologic findings and epidemiologic considerations
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DOI：
10.3201/eid0903.020219
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发表时间：
2003-03-01
影响因子：
11.8
通讯作者：
Mathiot, C
中科院分区：
文献类型：
--
作者：
Diallo, M;Ba, Y;Mathiot, C
经过8年的沉默后，登革热病毒血清型2（DENV-2）于1999年在塞内加尔东南部重新出现。1999年和2000年从森林走廊和周围村庄捕获的蚊子中分离出64株DENV-2菌株和9株DENV-2菌株。分离物获自先前描述的载体，叉尾伊蚊（Aedes furcifer），Ae. taylori，Ae. luteocephalus，和第一次在塞内加尔，从Ae。埃及伊蚊和埃及伊蚊。vittatus。在过去28年的昆虫学调查期间，对塞内加尔森林DENV-2爆发的回顾性分析表明，扩增是周期性的，具有5-8年的间隔和沉默间隔。森林化DENV-2的出现与降雨量之间没有相关性。对于森林中的DENV-2载体，降雨似乎特别影响雨季结束时（10月至11月）发生的病毒扩增。数据来自于对胚胎前（即，非成年）蚊子表明了一个次级传播循环，涉及先前确定为病媒的蚊子以外的蚊子。
After 8 years of silence, dengue virus serotype 2 (DENV-2) reemerged in southeastern Senegal in 1999. Sixty-four DENV-2 strains were isolated in 1999 and 9 strains in 2000 from mosquitoes captured in the forest gallery and surrounding villages. Isolates were obtained from previously described vectors, Aedes furcifer, Ae. taylori, Ae. luteocephalus, and-for the first time in Senegal-from Ae. aegypti and Ae. vittatus. A retrospective analysis of sylvatic DENV-2 outbreaks in Senegal during the last 28 years of entomologic investigations shows that amplifications are periodic, with intervening, silent intervals of 5-8 years. No correlation was found between sylvatic DENV-2 emergence and rainfall amount. For sylvatic DENV-2 vectors, rainfall seems to particularly affect virus amplification that occurs at the end of the rainy season, from October to November. Data obtained from investigation of preimaginal (i.e., nonadult) mosquitoes suggest a secondary transmission cycle involving mosquitoes other than those identified previously as vectors.