Nonmedical Use of Prescription Opioids among Pregnant US Women
Nonmedical Use of Prescription Opioids among Pregnant US Women
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DOI：
10.1016/j.whi.2017.03.001
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发表时间：
2017-05-01
影响因子：
3.2
通讯作者：
Patrick, Stephen W.
中科院分区：
文献类型：
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作者：
Kozhimannil, Katy B.;Graves, Amy J.;Patrick, Stephen W.
目的：妊娠期间非医疗使用阿片类药物与妇女和婴儿的不良结局有关，使其成为预防和识别的突出目标。使用全国代表性的样本，我们确定了美国的特点。在过去的一年或在过去month.Methods报告处方阿片类药物滥用的孕妇：我们使用的数据从全国药物使用和健康调查（2005-2014）在回顾性分析。样本包括8，721名（加权n = 23，855，041）年龄在12至44岁之间的非机构化妇女，她们在接受调查时报告怀孕。结果是在过去12个月和过去30天内非医疗使用处方阿片类药物。多变量logistic回归模型，以确定相关的非医疗阿片类药物的使用后，占潜在的混杂variables.Results：在美国的孕妇中，5.1%的报告非医疗阿片类药物的使用在过去的一年。在调整模型中，过去一年的抑郁或焦虑与过去一年的非医疗使用密切相关（校正比值比[AOR]，2.15; 95%CI，1.52-3.04），以及过去一年饮酒（AOR，1.56; 95%CI，1.11-2.17）、烟草（AOR，1.72; 95%CI，1.17-2.53）和大麻（AOR，3.44; 95%CI，2.47-4.81）。此外，0.9%的美国孕妇在过去一个月报告了非医疗阿片类药物的使用。过去一年的抑郁或焦虑和过去一个月使用的酒精，烟草和大麻各自独立预测过去一个月nonmedical use.Conclusions：与非医疗阿片类药物使用的孕妇相关的特征揭示了精神疾病和共同发生的物质使用的人群。改善筛查和治疗的政策和预防工作可以集中在本研究中确定的高危人群。(c)2017年，Jacobs Institute of Women’s Health。爱思唯尔公司出版
Objectives: Nonmedical use of opioids during pregnancy is associated with adverse outcomes for women and infants, making it a prominent target for prevention and identification. Using a nationally representative sample, we determined characteristics of U.S. pregnant women who reported prescription opioid misuse in the past year or during the past month.Methods: We used data from the National Survey on Drug Use and Health (2005-2014) in a retrospective analysis. The sample included 8,721 (weighted n = 23,855,041) noninstitutionalized women, ages 12 to 44, who reported being pregnant when surveyed. Outcomes were nonmedical use of prescription opioid medications during the past 12 months and during the past 30 days. Multivariable logistic regression models were created to determine correlates of nonmedical opioid use after accounting for potential confounding variables.Results: Among pregnant women in the United States, 5.1% reported nonmedical opioid use in the past year. In adjusted models, depression or anxiety in the past year was strongly associated with past year nonmedical use (adjusted odd ratio [AOR], 2.15; 95% CI, 1.52-3.04), as were past year use of alcohol (AOR, 1.56; 95% CI, 1.11-2.17), tobacco (AOR, 1.72; 95% CI, 1.17-2.53), and marijuana (AOR, 3.44; 95% CI, 2.47-4.81). Additionally, 0.9% of U.S. pregnant women reported nonmedical opioid use in the past month. Past year depression or anxiety and past month use of alcohol, tobacco, and marijuana each independently predicted past month nonmedical use.Conclusions: Characteristics associated with nonmedical opioid use by pregnant women reveal populations with mental illness and co-occurring substance use. Policy and prevention efforts to improve screening and treatment could focus on the at-risk populations identified in this study. (c) 2017 Jacobs Institute of Women's Health. Published by Elsevier Inc.