Simulations of chemical transport and reaction in a suspension of cells I: an augmented forcing point method for the stationary case

Simulations of chemical transport and reaction in a suspension of cells I: an augmented forcing point method for the stationary case
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细胞悬浮液中化学传递和反应的模拟 I:静止情况下的增强受力点方法

DOI:
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发表时间:
2012
期刊:
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通讯作者:
A. Fogelson
A. Fogelson
中科院分区:
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文献类型:
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作者:
Lingxing Yao;A. Fogelson

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提出了一种新的增广强迫点方法来解决化学物质在悬浮细胞外的流体中的输运问题,并与细胞表面的化学反应相耦合。在这种方法中,化学浓度和强迫函数值同时确定从增广系统的方程。该方法比预估-校正-型强迫点方法更稳定、更精确,与相应的鬼单元方法产生相同的解,计算成本低得多,并且即使对于密集的单元,也能提供在空间和时间上逐点二阶精度的解。版权所有© 2011约翰威利父子有限公司.
A novel augmented forcing point method is presented to solve the problem of chemical transport in the fluid outside of a collection of suspended cells coupled with chemical reactions on the surfaces of the cells. In this method, the chemical concentrations and the forcing function values are determined simultaneously from an augmented system of equations. The method is more stable and accurate than predictor‐corrector‐type forcing point methods, yields the same solution as a corresponding ghost cell method with much less computational cost, and provides solutions that are pointwise second‐order accurate in space and time, even for closely‐spaced cells. Copyright © 2011 John Wiley & Sons, Ltd.