Precise Assembly of Proteins and Carbohydrates for Next-Generation Biomaterials

Precise Assembly of Proteins and Carbohydrates for Next-Generation Biomaterials
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下一代生物材料的蛋白质和碳水化合物的精确组装

DOI:
10.1021/jacs.2c04418
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发表时间:
2022-08-31
影响因子:
15
通讯作者:
Chen, Guosong
Chen, Guosong
中科院分区:
化学1区
文献类型:
--
作者:
Li, Long;Chen, Guosong

文献摘要

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生物大分子的复杂性和多样性使其成为产生精确组装的独特类别的构建块。由于其固有的特性,如准确识别,自组织和适应性,它们特别适用于与生命系统集成的新一代生物材料。因此,已经开发了许多优秀的方法,导致了各种相当实用的结果。在这里,我们回顾了最近的进展,人工精确组装的制造和应用,采用蛋白质和碳水化合物作为积木,其次是我们的一些新的挑战,目标和未来的研究方向在这一领域的机遇的看法。
The complexity and diversity of biomacromolecules make them a unique class of building blocks for generating precise assemblies. They are particularly available to a new generation of biomaterials integrated with living systems due to their intrinsic properties such as accurate recognition, self-organization, and adaptability. Therefore, many excellent approaches have been developed, leading to a variety of quite practical outcomes. Here, we review recent advances in the fabrication and application of artificially precise assemblies by employing proteins and carbohydrates as building blocks, followed by our perspectives on some of new challenges, goals, and opportunities for the future research directions in this field.