Investigation of mechanisms linking depressed mood to nicotine dependence
Investigation of mechanisms linking depressed mood to nicotine dependence
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DOI：
10.1016/0306-4603(95)00032-1
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发表时间：
1996-01-01
影响因子：
4.4
通讯作者：
Caporaso, N
中科院分区：
文献类型：
--
作者：
Lerman, C;Audrain, J;Caporaso, N
本研究考察了寻求戒烟治疗的吸烟者抑郁情绪与尼古丁依赖水平之间的认知-行为联系。治疗前，202名受试者完成了吸烟史、抑郁症状、“自我用药”过程、“习得性无助”过程和尼古丁依赖的有效自我报告测量。结果显示，48%的研究人群在流行病学研究中心（CES-D）抑郁量表上得分在“抑郁”范围内。此外，这些吸烟者报告的尼古丁依赖程度明显高于其他非抑郁症吸烟者。在与习得性无助理论相关的几个认知方面，抑郁吸烟者和非抑郁吸烟者没有差异。然而，抑郁的吸烟者更有可能报告“自我药物治疗”过程（即减少消极影响吸烟和刺激吸烟）。此外，多变量回归和路径分析表明，消极影响减少吸烟和刺激吸烟是抑郁-尼古丁依赖关系的序贯中介。这些结果强调需要筛查寻求治疗的吸烟者的抑郁症状，并开发适合抑郁吸烟者需求的戒烟治疗。
The present study examined the cognitive-behavioral linkages between depressed mood and level of nicotine dependence in smokers seeking smoking cessation treatment. Prior to treatment, 202 subjects completed validated self-report measures of smoking history, depressive symptomatology, ''self medication'' processes, ''learned helplessness'' processes, and nicotine dependence. Results revealed that 48% of the study population scored in the ''depressed'' range on the Center for Epidemiologic Studies (CES-D) depression scale. Further, these smokers reported significantly higher levels of nicotine dependence than other nondepressed smokers. Depressed and nondepressed smokers did not differ with respect to several cognitions related to learned helplessness theory. However, depressed smokers were more likely to report ''self medication'' processes (i.e., negative affect reduction smoking and stimulation smoking). In addition, multivariable regression and path analyses suggested that negative affect reduction smoking and stimulation smoking are sequential mediators of the depression-nicotine dependence relationship. These results underscore the need to screen for depressive symptomatology among smokers seeking treatment, and to develop cessation treatments that are tailored to the needs of depressed smokers.