Walking parameters of older adults from a lower back inertial measurement unit, a 6-year longitudinal observational study.
Walking parameters of older adults from a lower back inertial measurement unit, a 6-year longitudinal observational study.
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老年人的步行参数来自下背部惯性测量单元，这是一项为期6年的纵向观察研究。
DOI：
10.3389/fnagi.2022.789220
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发表时间：
2022
影响因子：
4.8
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中科院分区：
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步态随着年龄的增长而变化，不同性别之间的步态也有所不同。惯性测量单元(IMU)可以在移动环境和大量人群中对步态进行准确的定量评估。这项研究的目的是提供基于IMU的步态参数的值，这些值来自于一项大型的老年人纵向队列研究。我们使用下背部IMU每隔一年测量一次步态参数，如速度、步长、时间、变异性和不对称性，这些步态参数来自老年人(四次访问：715/1102/1017/957名参与者)每隔一年进行一次自定步速20米步行。此外，我们还计算了步态参数与性别和年龄的关系。与男性相比，女性的步速、步长、步子时间、大步时间、摆动时间和站立时间都较低。纵向分析表明，在两年的评估期内，这些参数至少有部分恶化，特别是在男性和老年人。变异性和非对称性参数显示出与性别和年龄相关的不太清楚的模式。总而言之，我们的大型纵向数据集提供了第一个性别特定的信息，其中的参数对于检测与年龄相关的步态变化特别有希望，可以从下背部的IMU中提取。这一信息可能有助于未来研究性别和年龄对步态的影响的观察和治疗研究，以及研究年龄相关疾病的研究。
Gait changes during aging and differs between sexes. Inertial measurement units (IMUs) enable accurate quantitative evaluations of gait in ambulatory environments and in large populations. This study aims to provide IMU-based gait parameters’ values derived from a large longitudinal cohort study in older adults. We measured gait parameters, such as velocity, step length, time, variability, and asymmetry, from straight, self-paced 20-m walks in older adults (four visits: 715/1102/1017/957 participants) every second year over 6 years using an IMU at the lower back. Moreover, we calculated the associations of gait parameters with sex and age. Women showed lower gait speed, step length, step time, stride time, swing time, and stance time, compared to men. Longitudinal analyses suggest that these parameters are at least partly deteriorating within the assessment period of 2 years, especially in men and at an older age. Variability and asymmetry parameters show a less clear sex- and age-associated pattern. Altogether, our large longitudinal dataset provides the first sex-specific information on which parameters are particularly promising for the detection of age-related gait changes that can be extracted from an IMU on the lower back. This information may be helpful for future observational and treatment studies investigating sex and age-related effects on gait, as well as for studies investigating age-related diseases.