Post-licensure deployment of oral cholera vaccines: a systematic review.
Post-licensure deployment of oral cholera vaccines: a systematic review.
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DOI：
10.2471/blt.14.139949
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发表时间：
2014-12-01
影响因子：
11.1
通讯作者：
Sack DA
中科院分区：
文献类型：
--
作者：
Martin S;Lopez AL;Bellos A;Deen J;Ali M;Alberti K;Anh DD;Costa A;Grais RF;Legros D;Luquero FJ;Ghai MB;Perea W;Sack DA
描述和分析口服霍乱疫苗接种运动的特点;包括地点、目标人群、后勤、疫苗覆盖率和运送费用。我们检索了PubMed、世界卫生组织（WHO）网站和科克伦数据库，没有日期或语言限制。我们联系了公共卫生人员、该领域的专家和卫生部，并进行了有针对性的网络搜索。共有33份文件被纳入分析。越南将口服霍乱疫苗接种纳入其公共卫生方案，并在1997年至2012年期间接种了约1 090万剂疫苗。此外，在1997年至2014年期间，在世界各地的16个以上的运动中，接种了300多万剂世卫组织预先合格的两种口服霍乱疫苗。这些运动或者是先发制人，或者是被动反应，在各种条件下进行，例如在难民营或自然灾害中。两剂疫苗的估计覆盖率为目标人群的46%至88%。每名完全免疫者的分娩费用约为0.11-3.99美元。口服霍乱疫苗接种运动的经验继续增加。公共卫生官员可以借鉴这一经验，更频繁地开展口服霍乱疫苗接种运动。
To describe and analyse the characteristics of oral cholera vaccination campaigns; including location, target population, logistics, vaccine coverage and delivery costs. We searched PubMed, the World Health Organization (WHO) website and the Cochrane database with no date or language restrictions. We contacted public health personnel, experts in the field and in ministries of health and did targeted web searches. A total of 33 documents were included in the analysis. One country, Viet Nam, incorporates oral cholera vaccination into its public health programme and has administered approximately 10.9 million vaccine doses between 1997 and 2012. In addition, over 3 million doses of the two WHO pre-qualified oral cholera vaccines have been administered in more than 16 campaigns around the world between 1997 and 2014. These campaigns have either been pre-emptive or reactive and have taken place under diverse conditions, such as in refugee camps or natural disasters. Estimated two-dose coverage ranged from 46 to 88% of the target population. Approximate delivery cost per fully immunized person ranged from 0.11–3.99 United States dollars. Experience with oral cholera vaccination campaigns continues to increase. Public health officials may draw on this experience and conduct oral cholera vaccination campaigns more frequently.