Bladder cancer: Analysis of multi-detector row helical CT enhancement in pattern and accuracy in tumor detection and perivesical staging
Bladder cancer: Analysis of multi-detector row helical CT enhancement in pattern and accuracy in tumor detection and perivesical staging
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DOI：
10.1148/radiol.2313021253
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发表时间：
2004-06-01
期刊：
影响因子：
19.7
通讯作者：
Cho, KS
中科院分区：
文献类型：
--
作者：
Kim, JK;Park, SY;Cho, KS
目的：评估膀胱癌的增强模式以及多排螺旋计算机断层扫描（CT）在膀胱癌检测和分期中的准确性。 材料和方法：在20例患者中，通过扫描延迟为40、60、80和100秒获得的动态对比材料增强多相CT图像测量膀胱癌的衰减值。在 67 名患者中，通过覆盖膀胱的 60 秒扫描延迟（切片厚度，2.5 毫米；波束间距，1.5）和覆盖腹部的 180 秒扫描延迟（切片厚度，5 毫米；波束间距，1.5）获得 CT 数据。我们前瞻性地评估了 CT 图像，并将 CT 的结果与 的结果进行了比较。组织学检查。我们评估了癌症检出率、癌症检出的阳性预测值以及诊断膀胱周围浸润的敏感性和特异性。结果：60 秒（105 HU +/- 16）和 80 秒（97 HU +/- 15）延迟 CT 图像上膀胱癌的衰减值显着高于其他图像（P < .05）。 67 名患者的癌症检出率和癌症检出的阳性预测值分别为 97% 和 95%，而在 44 名患者中，经尿道膀胱电切术 (TURB) 和 CT 检查之间的时间间隔为 7 天或以上，癌症检出率和阳性预测值分别提高到 100% 和 100%。 67 例患者诊断膀胱周围侵犯的敏感性和特异性分别为 89% 和 95%，而 44 例 TURB 和 CT 检查之间的时间间隔为 7 天或以上的患者则分别提高到 92% 和 98%。 结论：膀胱癌倾向于在扫描延迟 60 秒时出现峰值强化。多排螺旋 CT 可用于膀胱癌的检测和分期。 (C) 北美放射学会，2004 年。
PURPOSE: To evaluate the enhancement pattern of bladder cancer and the accuracy of multi-detector row helical computed tomography (CT) in the detection and staging of bladder cancer.MATERIALS AND METHODS: In 20 patients, the attenuation value of bladder cancer was measured on dynamic contrast material-enhanced multiphasic CT images obtained with scanning delays of 40, 60, 80, and 100 seconds. In 67 patients, CT data were obtained with a 60-second scanning delay that covered the bladder (section thickness, 2.5 mm; beam pitch, 1.5) and a 180-second scanning delay that covered the abdomen (section thickness, 5 mm; beam pitch, 1.5). We prospectively evaluated CT images and compared findings at CT with findings at. histologic examination. We evaluated cancer detection rate, positive predictive value of cancer detection, and sensitivity and specificity in the diagnosis of perivesical invasion.RESULTS: The attenuation value of bladder cancers was significantly higher on 60-(105 HU +/- 16) and 80-second (97 HU +/- 15) delayed CT images than on the other images (P < .05). The cancer detection rate and positive predictive value for cancer detection were 97% and 95%, respectively, in 67 patients and increased to 100% and 100%, respectively, in 44 patients with a time interval of 7 or more days between transurethral resection of the bladder (TURB) and CT examination. Sensitivity and specificity in the diagnosis of perivesical invasion were 89% and 95%, respectively, in 67 patients and increased to 92% and 98%, respectively, in 44 patients with a time interval of 7 or more days between TURB and CT examination.CONCLUSION: Bladder cancer tends to show peak enhancement with the 60-second scanning delay. Multi-detector row helical CT is useful in the detection and staging of bladder cancer. (C) RSNA, 2004.