Macular hole formation in patients with retinitis pigmentosa and prognosis of pars plana vitrectomy
Macular hole formation in patients with retinitis pigmentosa and prognosis of pars plana vitrectomy
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色素性视网膜炎患者黄斑裂孔的形成与平坦部玻璃体切除术的预后
DOI：
10.1097/iae.0b013e31815ec341
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发表时间：
2008-04-01
影响因子：
3.3
通讯作者：
Nao-I, Nobuhisa
中科院分区：
文献类型：
--
作者：
Jin, Zi-Bing;Gan, De-Kang;Nao-I, Nobuhisa
目的：调查色素性视网膜炎（RP）患者黄斑裂孔（MH）的形成情况，并确定这些患者的手术预后。方法：回顾性分析了四例患有 MH 的 RP 患者的数据。进行了全面的眼部检查，包括视网膜电图、Goldmann 视野检查、彩色眼底检查、B 扫描超声断层扫描和光学相干断层扫描 (OCT)。所有患者均接受平面玻璃体切除术，然后剥离后内界膜并进行气体填塞。术前最佳矫正视力范围为20/1000至20/100。结果：3名患者的OCT显示典型的全层MH。其中两名患者患有玻璃体后脱离或玻璃体视网膜牵引；一名患者的另一只眼出现黄斑囊样水肿。第四名患者患有广泛的视网膜脱离；检眼镜检查发现黄斑区有一个洞。手术后，三名患者的视力显着改善；视网膜脱离患者受影响眼睛的视力没有变化。 OCT 显示 MH 已充分封闭。结论：我们报告了一项临床研究的结果，其中包括四名伴有 MH 的 RP 患者。玻璃体视网膜手术对于有效治疗 RP 中的 MH 是必要的。
Purpose: To investigate macular hole (MH) formation in patients with retinitis pigmentosa (RP) and to determine surgical prognosis for these patients.Methods: Data for four RP patients with MHs were retrospectively reviewed. Comprehensive ocular examinations, including electroretinography, Goldmann perimetry, color funduscopy, B-scan ultrasonic tomography, and optical coherence tomography (OCT), were performed. All patients underwent par plana vitrectomy followed by peeling of the posterior inner limiting membrane and gas tamponade. Preoperative best-corrected visual acuity ranged from 20/1000 to 20/100.Results: Typical full-thickness MHs were evident by OCT for three patients. Two of these patients had posterior vitreous detachment or vitreoretinal traction; one had cystoid macular edema in the fellow eye. A fourth patient had extensive retinal detachment; ophthalmoscopy revealed a hole in the macular region. After surgery, significant improvement of visual acuity was recorded for three patients; the patient with retinal detachment had no change in visual acuity in the affected eye. OCT showed adequate sealing of the MHs.Conclusions: We report results of a clinical investigation including four RP patients with concomitant MHs. Vitreoretinal surgery is necessary for effective management of MHs in RP.