The influence of initial outlines on manual segmentation.

The influence of initial outlines on manual segmentation.
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初始轮廓对手动分割的影响。

DOI:
10.1118/1.3392287
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发表时间:
2010
期刊:
影响因子:
3.8
通讯作者:
Armato3rd,SamuelG
Armato3rd,SamuelG
中科院分区:
医学3区
文献类型:
--
作者:
Sensakovic,WilliamF;Starkey,Adam;Roberts,Rachael;Straus,Christopher;Caligiuri,Philip;Kocherginsky,Masha;Armato3rd,SamuelG

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目的初始轮廓通常被用来帮助减少与手动分割和测量医学图像结构相关的时间成本。本研究评估了初始轮廓对观察者内手动分割和观察者间精确度的影响。方法三名观察者独立概述了 30 名患者扫描中每一次扫描中 5 个计算机断层扫描 (CT) 切片中存在的所有胸膜间皮瘤肿瘤。一段时间后,向每个观察者呈现相同系列的 CT 切片,并叠加每个观察者的轮廓作为初始轮廓。每个观察者通过改变初始轮廓来创建改变的轮廓,以反映他们对肿瘤边界的感知。使用杰卡德相似系数将改变的轮廓与原始轮廓进行比较。通过对值应用方差模型的线性混合效应分析来计算观察者轮廓的观察者内和观察者间精度。还记录了微小改变(仅导致初始轮廓发生轻微变化的改变)的百分比。结果观察者原始轮廓对之间的平均值为 0.371。当从相同的初始轮廓进行更改时,观察者轮廓对之间的平均值为 0.796,表明观察者间的精确度有所提高。通过改变观察者自己的初始轮廓和改变不同观察者的初始轮廓创建的观察者分割值之间的平均差异为 0.476,表明初始轮廓强烈影响观察者内的精度。观察者对 74.5% 的初始大纲进行了微小修改。结论观察者内和观察者间的精确度在很大程度上取决于初始大纲。这些影响可能是由于观察者倾向于只对最初的轮廓进行微小的修正。当初始轮廓用作观察者辅助时,这一发现可能会影响观察者研究设计、肿瘤生长评估、计算机辅助诊断系统验证和放射治疗靶区定义。
PurposeInitial outlines are often presented as an aid to reduce the time‐cost associated with manual segmentation and measurement of structures in medical images. This study evaluated the influence of initial outlines on manual segmentation intraobserver and interobserver precision.MethodsThree observers independently outlined all pleural mesothelioma tumors present in five computed tomography (CT) sections in each of 30 patient scans. After a lapse of time, each observer was presented with the same series of CT sections with the outlines of each observer superimposed as initial outlines. Each observer created altered outlines by altering the initial outlines to reflect their perception of the tumor boundary. Altered outlines were compared to original outlines using the Jaccard similarity coefficient. Intraobserver and interobserver precision of observer outlines were calculated by applying linear mixed effects analysis of variance models to the values. The percent of minor alterations (alterations that resulted in only slight changes in the initial outline) was also recorded.ResultsThe average value between pairs of observer original outlines was 0.371. The average value between pairs of observer outlines when altered from an identical initial outline was 0.796, indicating increased interobserver precision. The average difference between values of an observer's segmentation created by altering their own initial outline and when altering a different observer's initial outline was 0.476, indicating initial outlines strongly influence intraobserver precision. Observers made minor alterations on 74.5% of initial outlines with which they were presented.ConclusionsIntraobserver and interobserver precision were strongly dependent on the initial outline. These effects are likely due to the tendency of observers to make only minor corrections to initial outlines. This finding could impact observer study design, tumor growth assessment, computer‐aided diagnosis system validation, and radiation therapy target volume definition when initial outlines are used as an observer aid.
可以测量曲线的温度吗?
DOI: 10.1007/bf00280431
发表时间: 1986
影响因子: 2.5
作者:
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DOI: --
发表时间: 2004
期刊:
影响因子: --
作者:
B. Zheng;R. Swensson;Sara K Golla;C. Hakim;R. Shah;Luisa P. Wallace;D. Gur
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DOI: 10.1007/s00330-003-2027-0
发表时间: 2004-03-01
期刊: EUROPEAN RADIOLOGY
影响因子: 5.9
作者:
Monsky, WL;Raptopoulous, V;Ransil, BJ
通讯作者: Ransil, BJ