A historical perspective on colorectal liver metastases and peritoneal carcinomatosis: similar results, different treatments.
A historical perspective on colorectal liver metastases and peritoneal carcinomatosis: similar results, different treatments.
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DOI：
10.1016/s1055-3207(03)00046-2
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发表时间：
2003-07-01
影响因子：
1.9
通讯作者：
Gertsch, Philippe
中科院分区：
文献类型：
--
作者：
Gertsch, Philippe
腹膜转移癌和肝脏继发性癌之间的相似性使肿瘤学家将腹膜视为腹腔内结构，当发生播散性疾病时，可以像肝脏一样切除腹膜以达到治疗目的。现在必须认识到通过细胞减灭术和IPHC治疗腹膜癌转移的可能性。然而，需要来自对照研究的令人信服的数据来快速普遍接受这种治疗，从而为大量预后绝望的患者带来治愈的机会。这一事实，再加上缺乏符合明确治疗条件的腹膜癌病患者，强调了参考中心之间合作研究的必要性。
Similarities between peritoneal carcinomatosis and liver secondaries allow the oncologist to regard the peritoneum as an intraabdominal structure that can, like the liver, be resected with curative intent when disseminated disease has occurred. The possibility for cure of peritoneal carcinomatosis by cytoreductive surgery and IPHC must now be recognized. However, convincing data from controlled studies will be required for rapid general acceptance of this treatment, bringing, as a consequence, a chance of cure to a larger number of patients with a desperate prognosis. This fact, together with a scarcity of patients with peritoneal carcinomatosis eligible for definitive treatment, emphasizes the need for cooperative studies between centers of reference.