Life's Simple 7 and incidence of diabetes among American Indians: the Strong Heart Family Study.
Life's Simple 7 and incidence of diabetes among American Indians: the Strong Heart Family Study.
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DOI：
10.2337/dc13-2267
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发表时间：
2014-08
期刊：
影响因子：
16.2
通讯作者：
Siscovick DS
中科院分区：
文献类型：
--
作者：
Fretts AM;Howard BV;McKnight B;Duncan GE;Beresford SA;Mete M;Zhang Y;Siscovick DS
美国心脏协会对最佳健康的建议，总结在生活的简单7，与降低心血管疾病（CVD）相关终点的风险有关，但没有研究检查这些目标与2型糖尿病事件的关联，这与CVD的高风险有关。这项分析的目的是研究美国印第安人中，心脏代谢疾病的高风险人群中的糖尿病事件与生活的简单7个目标的关联。在基线时没有糖尿病的强心脏家族研究参与者（n = 1，639）和参加随访检查的参与者被纳入分析。根据Life's Simple 7目标，使用体力活动，饮食，BMI，吸烟，血压，空腹血糖和胆固醇指标创建0至7的风险评分。使用2003年美国糖尿病协会标准定义糖尿病，包括使用胰岛素或口服降糖药物或随访空腹血糖水平≥126 mg/dL。广义估计方程被用来检查风险评分与糖尿病事件的关联。在平均5年的随访期间（范围4-8年），我们确定了210例2型糖尿病患者。与达到0-1个目标的参与者相比，达到2-3或4+个目标的参与者患糖尿病的几率较低，比值比分别为0.40（95% CI 0.29-0.56）和0.11（95% CI 0.05-0.21）。采用两到三个简单的生活7目标与糖尿病风险降低有关。
The American Heart Association’s recommendations for optimal health, summarized in Life’s Simple 7, have been associated with reduced risk of cardiovascular disease (CVD)-related end points, but no studies have examined the association of these goals with incident type 2 diabetes, which is associated with high risk for CVD. The purpose of this analysis was to examine the associations of Life’s Simple 7 goals with incident diabetes among American Indians, a population at high risk of cardiometabolic diseases. Strong Heart Family Study participants without diabetes (n = 1,639) at baseline and who participated in a follow-up examination were included in the analysis. Risk scores ranging from 0 to 7 were created using physical activity, diet, BMI, smoking, blood pressure, fasting glucose, and cholesterol metrics in accordance with Life’s Simple 7 goals. Diabetes was defined using 2003 American Diabetes Association criteria, including use of insulin or oral antidiabetes medication or a follow-up fasting plasma glucose level ≥126 mg/dL. Generalized estimating equations were used to examine the association of risk scores with incident diabetes. During a mean 5-year follow-up (range 4–8 years), we identified 210 cases of incident type 2 diabetes. Compared with participants who achieved 0–1 goals, those who achieved 2–3 or 4+ goals had lower odds of diabetes, with odds ratios = 0.40 (95% CI 0.29–0.56) and 0.11 (95% CI 0.05–0.21), respectively. The adoption of as few as two or three Life’s Simple 7 goals is associated with a lower risk of diabetes.
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影响因子：
37.8
作者：
Shay CM;Ning H;Allen NB;Carnethon MR;Chiuve SE;Greenlund KJ;Daviglus ML;Lloyd-Jones DM
通讯作者：
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影响因子：
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影响因子：
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作者：
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