A non-contrast self-navigated 3-dimensional MR technique for aortic root and vascular access route assessment in the context of transcatheter aortic valve replacement: proof of concept
A non-contrast self-navigated 3-dimensional MR technique for aortic root and vascular access route assessment in the context of transcatheter aortic valve replacement: proof of concept
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DOI：
10.1007/s00330-015-3906-x
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发表时间：
2016-04-01
影响因子：
5.9
通讯作者：
De Cecco, Carlo N.
中科院分区：
文献类型：
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作者：
Renker, Matthias;Varga-Szemes, Akos;De Cecco, Carlo N.
目的：由于经导管主动脉瓣置换术（TAVR）患者肾功能衰竭的患病率较高，因此术前计划需要使用非对比MR技术。我们试图评价一种新的、无造影剂、自由呼吸、自导航三维（SN 3D）MR序列与无造影剂二维平衡稳态自由旋进相比，对主动脉根部至髂股流出段进行成像的可行性方法SN 3D（视野220-370 mm，层厚1.15 mm，重复/回波时间（TR/TE）3.1/1.5 ms，扫描时间1.5 ms）。和翻转角，115 A度]和2D-bSSFP采集10例健康受试者（FOV，340 mm，层厚6 mm，TR/TE，2.3/1.1 ms，翻转角77 A °（均为男性;平均年龄，30.3 A +/- 4.3岁）使用1.5 T MRI系统。结果2D-bSSFP和SN 3D的平均有效主动脉瓣环直径相似（26.7 +/- 0.7 vs. 26.1 +/- 0.9 mm，p = 0.23）。2D-bSSFP（4; IQR 3-4）的平均图像质量评级略高于（p = 0.03）SN 3D（3; IQR 2-4）。SN 3D成像的平均总采集时间为12.8 +/- 2.4 min。结论我们的研究结果表明，一种新的SN 3D序列允许快速，自由呼吸的主动脉根和腹髂股动脉系统的评估，而无需管理造影剂。
Objectives Due to the high prevalence of renal failure in transcatheter aortic valve replacement (TAVR) candidates, a non-contrast MR technique is desirable for pre-procedural planning. We sought to evaluate the feasibility of a novel, non-contrast, free-breathing, self-navigated three-dimensional (SN3D) MR sequence for imaging the aorta from its root to the iliofemoral run-off in comparison to non-contrast two-dimensional-balanced steady-state free-precession (2D-bSSFP) imaging.Methods SN3D [field of view (FOV), 220-370 mm(3); slice thickness, 1.15 mm; repetition/echo time (TR/TE), 3.1/1.5 ms; and flip angle, 115A degrees] and 2D-bSSFP acquisitions (FOV, 340 mm; slice thickness, 6 mm; TR/TE, 2.3/1.1 ms; flip angle, 77A degrees) were performed in 10 healthy subjects (all male; mean age, 30.3 A +/- 4.3 yrs) using a 1.5-T MRI system. Aortic root measurements and qualitative image ratings (four-point Likert-scale) were compared.Results The mean effective aortic annulus diameter was similar for 2D-bSSFP and SN3D (26.7 +/- 0.7 vs. 26.1 +/- 0.9 mm, p = 0.23). The mean image quality of 2D-bSSFP (4; IQR 3-4) was rated slightly higher (p = 0.03) than SN3D (3; IQR 2-4). The mean total acquisition time for SN3D imaging was 12.8 +/- 2.4 min.Conclusions Our results suggest that a novel SN3D sequence allows rapid, free-breathing assessment of the aortic root and the aortoiliofemoral system without administration of contrast medium.