Urinary incontinence and depression
Urinary incontinence and depression
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DOI：
10.1097/00005392-199907000-00020
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发表时间：
1999-07-01
影响因子：
6.6
通讯作者：
Steers, WD
中科院分区：
文献类型：
--
作者：
Zorn, BH;Montgomery, H;Steers, WD
目的：血清素能神经元系统与焦虑和抑郁有关。由于来自脑干的下降血清素通路抑制膀胱收缩，我们推测与血清素功能改变相关的抑郁症可能容易导致急迫性尿失禁。我们证明了抑郁症和特发性急迫性尿失禁之间的关联。材料和方法：将总共 115 名连续到失禁诊所就诊的失禁患者与 80 名失禁对照患者进行比较。询问患者的抑郁病史并完成贝克抑郁量表（BDI）。病例：根据病史和视频尿动力学将尿动力学分类为真正的压力性失禁 (36)、急迫性失禁 (44) 或混合性失禁 (35)。 结果：30% 的失禁患者和 17% 的对照者发现 BDI 大于 12 和/或有抑郁史（比值比 2.3，95% 置信区间 1.0 至 5.0，p = 0.044）。 60% 的特发性急迫性尿失禁患者有异常 BDI 或抑郁病史（p
Purpose: Serotonergic neuronal systems have been implicated in anxiety and depression. Because descending serotonin pathways from the brain stem inhibit bladder contractions, we postulated that depression associated with altered serotonin function may predispose to urge incontinence. We demonstrate an association between depression and idiopathic urge incontinence.Materials and Methods: A total of 115 consecutive incontinent patients presenting to an incontinence clinic were compared to 80 continent controls. Patients were queried for a history of depression and completed a Beck Depression Inventory (BDI). Cases were:classified by history and video urodynamics as genuine stress (36), urge (44) or mixed (35) incontinence.Results: A BDI of greater than 12 and/or a history of depression was noted in 30% of incontinent patients and 17% of controls (odds ratio 2.3, 95% confidence interval 1.0 to 5.0, p = 0.044). An abnormal BDI or history of depression was revealed in 60% of patients with idiopathic urge incontinence (p