Familial resemblances in alcohol use: Genetic or cultural transmission?
Familial resemblances in alcohol use: Genetic or cultural transmission?
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DOI：
10.15288/jsa.1996.57.19
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发表时间：
1996-01-01
期刊：
影响因子：
--
通讯作者：
Boomsma, DI
中科院分区：
文献类型：
--
作者：
Koopmans, JR;Boomsma, DI
目的：父母和子女饮酒相似性可能是由于文化传播和遗传。我们研究了酒精使用的家族遗传和环境决定因素。方法：父母双胞胎的设计之间的遗传效应的贡献，兄弟姐妹共享的环境影响和文化传播的影响，从父母到后代的区别。通过问卷调查，从403个有15-16岁双胞胎的荷兰家庭和805个有17岁及以上双胞胎的家庭中获得了关于受试者是否曾经饮酒的数据。结果：15-16奥尔兹的父母与子女之间的相似性既可由遗传因素解释，也可由文化因素解释。共享的环境解释了青少年饮酒的58%至88%的个体差异。对于17岁及以上的双胞胎，43%的酒精使用个体差异可归因于遗传因素，37%归因于共享环境。在这个年龄组中没有文化传播的证据。结论：对于17岁及以上的青少年，父母饮酒并没有创造一个刺激儿童饮酒的环境。父母和17岁及以上子女之间饮酒的相似性可以通过他们的遗传相关性来解释。对于15-16岁的青少年，共享的环境影响比年龄较大的青少年更重要。只有10%的这种共享的环境变量可能会受到影响，由于文化传播的父母饮酒。
Objective: Resemblances between parents and children for alcohol use can be due both to cultural transmission and genetic inheritance. We examined the genetic and environmental determinants of the familial resemblances in alcohol use. Method: With a parent-twin design a distinction was made between the contribution of genetic effects, the environmental influences shared by siblings and the effects of cultural transmission from parents to offspring. By questionnaire, data on whether subjects had ever used alcohol were obtained from 403 Dutch families with a twin aged 15-16 years old and from 805 families with a twin aged 17 years and older. Results: For 15-16 year olds, the resemblance between parents and offspring could be explained either by genetic inheritance or cultural transmission. Shared environment explained between 58% and 88% of the individual differences in adolescent alcohol use. For twins aged 17 years and older, 43% of the individual differences in alcohol use could be attributed to genetic factors and 37% to shared environment. There was no evidence for cultural transmission in this age group. Conclusions: For adolescents aged 17 years and older, parental alcohol use did not create an environment that stimulated alcohol use in children. The resemblance for alcohol use between parents and their children aged 17 years and older could be explained by their genetic relatedness. For 15-16 year old adolescents, shared environmental influences were more important than for older adolescents. Only 10% of this shared environmental variance might be influenced by parental alcohol use due to cultural transmission.